Gender difference in relationship between anxiety-related personality traits and cerebral brain glucose metabolism

Abstract Recent functional neuroimaging studies have suggested that specific brain regions might be associated with the formation of anxiety-related personality traits, which are well known to be influenced by gender. Such anxiety-related personality traits are one of the representative predisposing...

Full description

Saved in:
Bibliographic Details
Published in:Psychiatry research. Neuroimaging 2009-09, Vol.173 (3), p.206-211
Main Authors: Hakamata, Yuko, Iwase, Mikio, Iwata, Hiroshi, Kobayashi, Toshiki, Tamaki, Tsuneo, Nishio, Masami, Matsuda, Hiroshi, Ozaki, Norio, Inada, Toshiya
Format: Article
Language:English
Subjects:
Adult
Affectivity. Emotion
Aged
Anxiety
Anxiety - diagnostic imaging
Anxiety - metabolism
Anxiety - pathology
Anxiety - psychology
Biological and medical sciences
Brain Mapping
FDG-PET
Female
Fluorodeoxyglucose F18
Fundamental and applied biological sciences. Psychology
Glucose - metabolism
Healthy subjects
Humans
Magnetic Resonance Imaging - methods
Male
Middle Aged
Personality
Personality Assessment
Personality traits
Personality. Affectivity
Positron-Emission Tomography - methods
Prefrontal Cortex - metabolism
Psychiatry
Psychology. Psychoanalysis. Psychiatry
Psychology. Psychophysiology
Radiology
Sex Factors
Sex specificity
TCI
Temperament
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract Recent functional neuroimaging studies have suggested that specific brain regions might be associated with the formation of anxiety-related personality traits, which are well known to be influenced by gender. Such anxiety-related personality traits are one of the representative predisposing factors for mood and anxiety disorders, whose incidence is also known to be much influenced by gender. However, little is known about the gender differences in brain function related to anxiety-related personality traits. The aim of the present study was to examine gender-related differences in the pattern of the relationships between an anxiety-related personality trait and cerebral brain glucose metabolism. Regional brain glucose metabolism was measured using [18 F]fluorodeoxyglucose positron emission tomography in 102 healthy subjects (65 males and 37 females). An anxiety-related trait was assessed using the Temperament and Character Inventory dimension Harm Avoidance (HA). HA was negatively correlated with glucose metabolism in the anterior portion of the ventromedial prefrontal cortex (vmPFC) in females but not in males. The anterior vmPFC may be a possible neural target for the prevention or therapy of emotional disorders, especially in females.
ISSN:0925-4927
1872-7506
DOI:10.1016/j.pscychresns.2008.10.002