A model of event-related EEG synchronization changes in beta and gamma frequency bands

• Published in: Journal of theoretical biology 2006-02, Vol.238 (4), p.901-913
• Main Authors: Grabska-Barwińska, Agnieszka, Zygierewicz, Jarosław
• Format: Article
• Language: English
• Subjects: Beta rebound; Beta Rhythm; Brain - physiology; Cortical circuit; EEG; Electroencephalography; Humans; Interneurons - physiology; Lumped model; Models, Neurological; Movement - physiology; Neuronal Plasticity; Pyramidal Cells - physiology; Signal Processing, Computer-Assisted
• ISSN: 0022-5193; 1095-8541
• DOI: 10.1016/j.jtbi.2005.07.001

During preparation, execution and recovery from simple movements, the EEG power spectrum undergoes a sequence of changes. The power in the beta band (13–25 Hz) decreases during preparation and execution of movement, but during recovery it reaches a level higher than that in the reference period (not affected by the event). These effects are known as event-related beta desynchronization and beta rebound. The power in the gamma band ( > 30 Hz ) increases significantly just before the onset of the movement. This effect is known as event-related gamma synchronization. There are numerous observations concerning these effects but the underlying physiological mechanisms and functional role are not clear. We propose a lumped computational model of a cortical circuit. The model consists only of a pyramidal and an interneuronal population. Each population represents averaged properties of constituting neurons. The output of the model represents a local field potential, with a power spectrum peak either in the beta or in the gamma band. The model elucidates the mechanisms of transition between slower and faster rhythms, gamma synchronization and beta desynchronization and rebound effects. The sufficient conditions to observe the effects in the model are changes of the external excitation level and of the connection strength between excitatory and inhibitory populations attributed to short-time plasticity. The present model presents the role of the pyramidal neurons to interneuron connection in the oscillatory behavior of the two populations. We conclude that the pronounced facilitation of the pyramidal to fast spiking interneuron connections, initiated by robust excitation of the motor cortex neurons, may be essential for the effect of beta rebound. Further experiments concerning short-time plasticity during behavioral tasks would be of great value in studies of functional local cortical circuits.