A Novel Route to Dipeptides via Noncondensation of Amino Acids:  2-Aminoperfluoropropene as a Synthon for Trifluoroalanine Dipeptides

2-Aminoperfluoropropene has been prepared by the Mg-promoted defluorinative N-silylation of N - p-methoxyphenyl hexafluoroacetone imine and has been employed as a synthon of trifluoroalanine for the preparation of trifluoroalanine dipeptides.

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Published in:Organic letters 2006-03, Vol.8 (5), p.827-829
Main Authors: Guo, Yong, Fujiwara, Kana, Uneyama, Kenji
Format: Article
Language:English
Subjects:
Alanine - analogs & derivatives
Alanine - chemistry
Amino Acids - chemistry
Combinatorial Chemistry Techniques
Dipeptides - chemical synthesis
Dipeptides - chemistry
Fluorocarbons - chemistry
Magnesium - chemistry
Molecular Structure
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cited_by cdi_FETCH-LOGICAL-a379t-7cfcf1a98056e240f4048b339ae779c33fa12501446a97e46997058d971c21f13
cites cdi_FETCH-LOGICAL-a379t-7cfcf1a98056e240f4048b339ae779c33fa12501446a97e46997058d971c21f13
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Uneyama, Kenji
description 2-Aminoperfluoropropene has been prepared by the Mg-promoted defluorinative N-silylation of N - p-methoxyphenyl hexafluoroacetone imine and has been employed as a synthon of trifluoroalanine for the preparation of trifluoroalanine dipeptides.
doi_str_mv 10.1021/ol0526726
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source American Chemical Society:Jisc Collections:American Chemical Society Read & Publish Agreement 2022-2024 (Reading list)
subjects Alanine - analogs & derivatives
Alanine - chemistry
Amino Acids - chemistry
Combinatorial Chemistry Techniques
Dipeptides - chemical synthesis
Dipeptides - chemistry
Fluorocarbons - chemistry
Magnesium - chemistry
Molecular Structure
title A Novel Route to Dipeptides via Noncondensation of Amino Acids:  2-Aminoperfluoropropene as a Synthon for Trifluoroalanine Dipeptides
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