A blood donor with bacteraemia

The major cause of platelet contamination is usually normal skin flora,1 which can be introduced at the time of blood collection. Donor bacteraemia is less likely, though it can occur after dental manipulation such as tooth extraction, tooth brushing, or use of gum irrigation devices.1 S bovis is no...

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Bibliographic Details
Published in:The Lancet (British edition) 2005-04, Vol.365 (9470), p.1596-1596
Main Authors: Haimowitz, Marcia D, Hernandez, Louis A, Herron, Ross M
Format: Article
Language:English
Subjects:
Adenocarcinoma - diagnosis
Adenocarcinoma - microbiology
Bacteremia - complications
Bacteremia - diagnosis
Bacteria
Bacterial diseases
Bacterial sepsis
Biological and medical sciences
Blood
Blood & organ donations
Blood Donors
Contamination
Female
Flora
General aspects
Human bacterial diseases
Humans
Infectious diseases
Medical sciences
Medical screening
Middle Aged
Sigmoid Neoplasms - diagnosis
Sigmoid Neoplasms - microbiology
Streptococcal Infections - complications
Streptococcal Infections - diagnosis
Streptococcus bovis
Teeth
Transfusion
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Summary:The major cause of platelet contamination is usually normal skin flora,1 which can be introduced at the time of blood collection. Donor bacteraemia is less likely, though it can occur after dental manipulation such as tooth extraction, tooth brushing, or use of gum irrigation devices.1 S bovis is not typical skin flora or a ubiquitous environmental agent. S bovis bacteraemia has been found in association with gastrointestinal neoplasia (ranging from colonic polyps to cancer), extracolonic malignancies, liver disease, endocarditis, cholangitis, meningitis, and diabetes mellitus.2-4 The American Society of Hematology and American Association of Blood Banks has published guidelines on the regulation of bacterial contamination of blood components,1 recently updated to include measures to detect and limit bacterial contamination in all platelet components.5 Bacterial sepsis related to transfusion is the second most frequent transfusion-related cause of fatalities in the USA.5
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(05)66462-8