Clinical neurological abnormalities in young adults with Asperger syndrome

Children with Asperger syndrome (AS), a neurodevelopmental disorder falling in the autism spectrum disorders, have an increased rate of neurological abnormalities, especially in motor coordination. While AS is a lifelong condition, little is known about the persistence of neurological abnormalities...

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Bibliographic Details
Published in:Psychiatry and clinical neurosciences 2006-04, Vol.60 (2), p.253-255
Main Authors: TANI, PEKKA, LINDBERG, NINA, APPELBERG, BJÖRN, NIEMINEN‐VON WENDT, TAINA, VON WENDT, LENNART, PORKKA‐HEISKANEN, TARJA
Format: Article
Language:English
Subjects:
Adult
Asperger syndrome
Asperger Syndrome - epidemiology
Asperger Syndrome - physiopathology
Asperger's syndrome
Autistic spectrum disorders
Biological and medical sciences
Brain - abnormalities
Brain - physiopathology
Child clinical studies
Children
Developmental disorders
Humans
Infantile autism
Medical sciences
Neurologic Examination
neurological abnormalities
Neurological disorders
neurological soft signs
Prevalence
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Severity of Illness Index
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Summary:Children with Asperger syndrome (AS), a neurodevelopmental disorder falling in the autism spectrum disorders, have an increased rate of neurological abnormalities, especially in motor coordination. While AS is a lifelong condition, little is known about the persistence of neurological abnormalities in adulthood. Twenty young adults with AS were compared with 10 healthy controls using a structured clinical neurological rating scale. The score for neurological abnormalities was higher in the AS group. In addition, a subscore for neurological soft signs indicating defective functioning of the central nervous system with a non‐localizing value was significantly higher in the AS subjects. This preliminary study indicates that neurological abnormalities, soft signs in particular, represent a non‐specific vulnerability factor for AS. Consistent with other features of AS, neurological abnormalities seem to persist into adulthood.
ISSN:1323-1316
1440-1819
DOI:10.1111/j.1440-1819.2006.01494.x