Compound changes and tooth mineralization effects of glass ionomer cements containing bioactive glass (S53P4), an in vivo study

In this study, modifications of glass ionomer cements (GICs) were made by adding bioactive glass (BAG) to GIC to obtain bioactive restorative materials. This study used SEM, EDS and visual analysis to examine the bioactivity and the ability of the study materials to mineralize dentin. Conventional c...

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Bibliographic Details
Published in:Biomaterials 2005-10, Vol.26 (30), p.5934-5941
Main Authors: Yli-Urpo, H, Narhi, M, Narhi, T
Format: Article
Language:English
Subjects:
Analysis of Variance
Animals
Bioactive glass
Biocompatible Materials
Calcium Compounds - chemistry
Composite Resins
Compressive Strength
Dental Bonding
Dental Cements - chemistry
Dental Stress Analysis
Dentin - chemistry
Dentin-Bonding Agents - chemistry
Dogs
Fluorides - chemistry
Glass - chemistry
Glass ionomer
Glass Ionomer Cements - chemistry
Hardness
Hydrogen-Ion Concentration
In vivo test
Light
Materials Testing
Microscopy, Electron, Scanning
Oxides - chemistry
Phosphorus Compounds - metabolism
Powders
Resin Cements - chemistry
SEM
Silicon Dioxide - chemistry
Surface Properties
Time Factors
Tooth
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Summary:In this study, modifications of glass ionomer cements (GICs) were made by adding bioactive glass (BAG) to GIC to obtain bioactive restorative materials. This study used SEM, EDS and visual analysis to examine the bioactivity and the ability of the study materials to mineralize dentin. Conventional cure and resin-modified light-curing GIC were used. The materials consisted of powder and liquid. Three experimental materials were made by mixing 10–30 wt% of BAG powder with GIC powders. Commercially available GIC without BAG were used as controls. Class III restorations were made in altogether 62 intact beagle dog teeth, and the operation was performed under general anesthesia. The restorations were followed clinically for 1, 3 or 6 weeks. Resin-modified GIC containing BAG showed uniform CaP surface formation on the restorations. Mineral depositions in the close vicinity of the restoration–dentin interface and in deeper parts of dentin tubules were also noticed in resin-modified GIC containing BAG particles. It can be concluded that resin-modified GIC containing BAG have good potential in clinical applications where enhanced mineralization is expected.
ISSN:0142-9612
1878-5905
DOI:10.1016/j.biomaterials.2005.03.008