CNS neurons with links to both mood-related cortex and sympathetic nervous system

Cardiovascular changes occur during mental stress and in certain types of mood disorders. The neural basis for this phenomenon is unknown but it may be dependent on CNS neurons that provide branched projections to affective processing regions of the brain, such as the medial prefrontal cortex, and t...

Full description

Saved in:
Bibliographic Details
Published in:Brain research 2005-07, Vol.1050 (1), p.199-202
Main Authors: Krout, Karl E., Mettenleiter, Thomas C., Karpitskiy, Vladimir, Van Nguyen, Xay, Loewy, Arthur D.
Format: Article
Language:English
Subjects:
Affect - physiology
Animals
Arousal
Biological and medical sciences
Blood pressure
Brain Mapping
Emotion
Emotions - physiology
Fundamental and applied biological sciences. Psychology
Herpesvirus 1, Suid
Hypothalamic
Hypothalamic Area, Lateral - cytology
Hypothalamic Area, Lateral - physiology
Neural Pathways
Nucleus tractus solitarius
Orexin
Peripheral nervous system. Autonomic nervous system. Neuromuscular transmission. Ganglionic transmission. Electric organ
Prefrontal Cortex - cytology
Prefrontal Cortex - physiology
Preoptic Area - cytology
Preoptic Area - physiology
Rats
Sleep
Sleep. Vigilance
Solitary Nucleus - cytology
Solitary Nucleus - physiology
Sympathetic Nervous System - cytology
Sympathetic Nervous System - physiology
Vertebrates: nervous system and sense organs
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Cardiovascular changes occur during mental stress and in certain types of mood disorders. The neural basis for this phenomenon is unknown but it may be dependent on CNS neurons that provide branched projections to affective processing regions of the brain, such as the medial prefrontal cortex, and to the sympathetic outflow system. Because these putative neurons may be connected to these two target sites by chains of neurons, we performed double virus transneuronal tracing experiments and show here that a select subset of neurons in the medial preoptic nucleus (MPN), lateral hypothalamic area (LHA), and nucleus tractus solitarius (NTS) are co-linked to these two sites. Neurotensin MPN, orexin-containing LHA, and catecholamine NTS neurons were the major phenotypes involved in these projections. This novel class of neurons may coordinate cardiovascular changes seen in different emotional states.
ISSN:0006-8993
1872-6240
DOI:10.1016/j.brainres.2005.04.090