EFFECTS OF STAGE AND DEGREE OF RESTRICTED FEEDING ON PREGNANCY OUTCOME IN RABBITS

This study's aim is to investigate the relationship between stage and degree of restricted feeding during the gestation period and occurrence of abortion, premature birth or fetal damage in rabbits. The study was composed of 5 groups of pregnant Kbl:NZW rabbits that consisted of 8 animals each....

Full description

Saved in:
Bibliographic Details
Published in:Journal of toxicological sciences 2006, Vol.31(2), pp.169-175
Main Authors: MATSUOKA, Tetsuya, MIZOGUCHI, Yasumoto, SERIZAWA, Kotaro, ISHIKURA, Toshikazu, MIZUGUCHI, Hiroyasu, ASANO, Yuzo
Format: Article
Language:English
Subjects:
Animals
Congenital Abnormalities - embryology
Embryonic Development - physiology
Female
Fetal Development - physiology
Food Deprivation - physiology
Pregnancy
Pregnancy Outcome
Pregnancy, Animal - physiology
Rabbits
Reproduction - physiology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:This study's aim is to investigate the relationship between stage and degree of restricted feeding during the gestation period and occurrence of abortion, premature birth or fetal damage in rabbits. The study was composed of 5 groups of pregnant Kbl:NZW rabbits that consisted of 8 animals each. These groups were subjected to restricted feeding in the following ways: (A) control group, free access to food, (B) 60 g per day from gestational days (GD) 6 to 18 (middle period), (C) 20 g per day from GD 6 to 18, (D) 20 g per day from GD 19 to 28 (post-middle period), and (E) 20 g per day from GD 6 to 28 (middle and post-middle periods). Even though all dams in Groups A, B and C went to full term, abortion or premature birth occurred to 2/8 and 8/8 dams in Groups D and E, respectively. Fetal lethality increased in Group C, which was subjected to restricted feeding at 20 g/head/day in the middle period. Slight inhibition of fetal growth was recorded only in Group D, which was subjected to restricted feeding in the post-middle period. Restricted feeding at 20 g/head/day in the middle period induced no abortion or premature birth, but increased fetal lethality that in the middle and post-middle periods resulted in abortion or premature birth of all dams, and that in the post-middle period resulted in abortion or premature birth at low incidence and slightly inhibited fetal growth. These results demonstrated that the post-middle period is vulnerable to effects of reduced food consumption in pregnant rabbits.
ISSN:0388-1350
1880-3989
DOI:10.2131/jts.31.169