Physiologic response of the six‐minute walk test in children with juvenile idiopathic arthritis

• Published in: Arthritis and rheumatism 2005-06, Vol.53 (3), p.351-356
• Main Authors: Paap, E., Net, J. van der, Helders, P. J. M., Takken, T.
• Format: Article
• Language: English
• Subjects: 6‐minute walk test; Adolescent; Anthropometry; Arthritis, Juvenile - physiopathology; Biological and medical sciences; Child; Children; Diseases of the osteoarticular system; Exercise Test; Female; Heart Rate - physiology; Humans; Inflammatory joint diseases; JIA; Male; Medical sciences; Physiologic response; Physiology; Walking - physiology
• ISSN: 0004-3591; 0893-7524; 1529-0131; 1529-0123
• DOI: 10.1002/art.21175

Objective To determine the physiologic response of the 6‐minute walk test (6‐mwt) in children with juvenile idiopathic arthritis (JIA). Methods Eighteen children with JIA (age 7–17 years; 6 boys, 12 girls) performed a 6‐mwt and a maximal exercise test. Results The physiologic response of the 6‐mwt was on average between 80% and 85% of the peak values of heart rate and oxygen uptake (VO2peak) during the maximal exercise test, except for the minute ventilation, which had a mean percentage of 68.5%. Backward regression analysis showed that height and distance walked were the best predictors of VO2peak during cycling (R2 = 0.883, P < 0.001). During the 6‐mwt, the difference between the first and second minute was significant in every variable, except for heart rate. The range of walking distance of children with JIA was comparable with that of healthy elderly people. Conclusion The physiologic response of the 6‐mwt is at a submaximal, intense level of exercise. The course of the responses during the 6‐mwt was normal. The 6‐mwt can be regarded as a good test for measuring functional exercise capacity.