Comparison of outcomes of percutaneous coronary interventions in patients of three age groups (<60, 60 to 80, and >80 years) (from the New York state angioplasty registry†)

• Published in: The American journal of cardiology 2006-11, Vol.98 (10), p.1334-1339
• Main Authors: FELDMAN, Dmitriy N, GADE, Christopher L, SLOTWINER, Alexander J, PARIKH, Manish, BERGMAN, Geoffrey, CHIU WONG, S, MINUTELLO, Robert M
• Format: Article
• Language: English
• Subjects: Age differences; Age Factors; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary - statistics & numerical data; Biological and medical sciences; Cardiology. Vascular system; Cardiovascular disease; Chi-Square Distribution; Comorbidity; Comparative analysis; Coronary Disease - epidemiology; Coronary Disease - therapy; Coronary heart disease; Diseases of the cardiovascular system; Female; Heart; Hospital Mortality; Humans; Logistic Models; Male; Medical sciences; Medical treatment; Middle Aged; New York - epidemiology; Outcome Assessment (Health Care); Prognosis; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects); Risk Factors
• ISSN: 0002-9149; 1879-1913
• DOI: 10.1016/j.amjcard.2006.06.026

Octogenarians have been under-represented in percutaneous coronary intervention (PCI) trials despite an increase in referrals for PCI. As the United States population ages, the number of high-risk PCIs in the elderly will continue to increase. This study investigated the effect of age on short-term prognosis after PCI in 3 age groups. Using the 2000/2001 New York State Angioplasty Registry, we compared in-hospital mortality and major adverse cardiac events (MACEs; death, stroke, or coronary artery bypass grafting) in emergency and elective PCI cohorts across 3 age categories of patients: 10,964 patients who underwent emergency PCI (80 years of age, n = 671) and 71,176 patients who underwent elective PCI (80 years of age, n = 5,782). Patients were considered to have undergone an emergency PCI if they had an acute myocardial infarction within 24 hours, had thrombolytic therapy within 7 days, or presented with hemodynamic instability or shock. Elderly patients had more co-morbidities, including more extensive coronary atherosclerosis, hypertension, peripheral vascular disease, and renal insufficiency, and presented more frequently with hemodynamic instability or shock. In the emergency PCI group, in-hospital mortality (1.0% vs 4.1% vs 11.5%, p