Screening and diagnosis of prediabetes: where are we headed

It is currently estimated that more than 300 million people have impaired glucose tolerance (IGT), putting them at increased risk for type 2 diabetes mellitus (T2DM) and its adverse consequences. In addition, many others are at risk on the basis of a family history of T2DM, obesity, dyslipidaemia an...

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Bibliographic Details
Published in:Diabetes, obesity & metabolism obesity & metabolism, 2007-09, Vol.9 (s1), p.12-16
Main Author: Alberti, K.G.M.M
Format: Article
Language:English
Subjects:
Blood Glucose - analysis
Diabetes Mellitus, Type 2 - blood
fasting plasma glucose testing
Glucose Intolerance - blood
Glucose Intolerance - diagnosis
Humans
impaired glucose tolerance
noninsulin-dependent diabetes mellitus
oral glucose tolerance testing
Overweight
prediabetes
Prediabetic State - blood
Prediabetic State - diagnosis
risk assessment
Risk Factors
type 2 diabetes
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Summary:It is currently estimated that more than 300 million people have impaired glucose tolerance (IGT), putting them at increased risk for type 2 diabetes mellitus (T2DM) and its adverse consequences. In addition, many others are at risk on the basis of a family history of T2DM, obesity, dyslipidaemia and hypertension. Screening for risk should include both blood glucose testing in high-risk populations and prescreening (e.g. by questionnaire, waist circumference measurement) to identify high-risk individuals in overall low-risk populations; these individuals should then undergo glucose testing. Fasting plasma glucose measurement cannot diagnose IGT; the preferred definite test for diagnosis is oral glucose tolerance testing.
ISSN:1462-8902
1463-1326
DOI:10.1111/j.1463-1326.2007.00764.x