Decision-making and breast cancer clinical trials How experience challenges attitudes

The aim of this study was to measure women's preferences about decision-making and their impact to participate or not to a hypothetical randomised controlled trial (RCT). We surveyed prospectively breast cancer patients invited to participate in a clinical RCT (group 1a=201 acceptances, group 1...

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Bibliographic Details
Published in:Contemporary clinical trials 2007-11, Vol.28 (6), p.684-694
Main Authors: MANCINI, Julien, GENEVE, Jean, JIMENEZ, Marta, TARPIN, Carole, REYNIER, Claire Julian, DALENC, Florence, GENRE, Dominique, MONNIER, Alain, KERBRAT, Pierre, LARGILLIER, Rémy, SERIN, Daniel, RIOS, Maria, ROCHE, Henri
Format: Article
Language:English
Subjects:
Adult
Attitude
Biological and medical sciences
Breast Neoplasms
Clinical trial. Drug monitoring
Clinical Trials as Topic
Decision Making
Female
France
General pharmacology
Gynecology. Andrology. Obstetrics
Health Care Surveys
Humans
Mammary gland diseases
Medical sciences
Middle Aged
Patient Participation - psychology
Pharmacology. Drug treatments
Prospective Studies
Randomized Controlled Trials as Topic
Tumors
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Summary:The aim of this study was to measure women's preferences about decision-making and their impact to participate or not to a hypothetical randomised controlled trial (RCT). We surveyed prospectively breast cancer patients invited to participate in a clinical RCT (group 1a=201 acceptances, group 1b=66 refusals) or not invited (group 2=188). All women had the same treatment. Decision-making preferences of patients who had refused clinical RCT entry were more patient's centred (72.3%) compared to those of patients who accepted (35.0%, P
ISSN:1551-7144
1559-2030
DOI:10.1016/j.cct.2007.03.001