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Lessons from the clinical course of IgE-mediated cow milk allergy in Israel
Cow milk and milk products are the most common food products consumed in Israel; rates of allergy to cow milk exceed those of peanuts in infants and children. The aim of the present study was to evaluate retrospectively the clinical features and natural course of immunoglobulin (Ig) E‐mediated cow m...
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Published in: | Pediatric allergy and immunology 2007-11, Vol.18 (7), p.589-593 |
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Main Authors: | , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | Cow milk and milk products are the most common food products consumed in Israel; rates of allergy to cow milk exceed those of peanuts in infants and children. The aim of the present study was to evaluate retrospectively the clinical features and natural course of immunoglobulin (Ig) E‐mediated cow milk allergy (CMA) in Israel. Data of children diagnosed with CMA from 1995 to 2003, were collected regarding age at first and most recent reactions, symptoms and signs, family history of atopy, other allergic diseases, emergency department visits, hospitalizations, and treatment. Patients with transient CMA were compared to those with persistent CMA (≥3 yr old). The study group consisted of 105 patients, 43 with transient CMA (age range: 0.48–11 yr). The remaining 62 patients (age range: 3–16.5 yr) did not achieve tolerance to cow milk during the follow‐up period. No differences were found between the groups in mean age and symptoms and signs at the first allergic reaction and family history of atopy. Patients with persistent CMA had a higher rate of asthma than patients with transient CMA (61.2% vs. 18.6%, p |
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ISSN: | 0905-6157 1399-3038 |
DOI: | 10.1111/j.1399-3038.2007.00562.x |