Comparative study of spinal motoneuron axon collaterals

Numerous spinal motoneurons in mammals possess recurrent axon collaterals included in a feedback loop for controlling motoneuron activity. For nonmammalian vertebrates, the data concerning the existence of collaterals and their intraspinal branching are fragmentary and contradictory. We focused on a...

Full description

Saved in:
Bibliographic Details
Published in:Brain research bulletin 2005-09, Vol.66 (4), p.381-386
Main Authors: Chmykhova, N.M., Adanina, V.O., Karamian, O.A., Kozhanov, V.M., Vesselkin, N.P., Clamann, H.-P.
Format: Article
Language:English
Subjects:
Animals
Anura
Axon collateral
Axons - physiology
Feedback - physiology
Horseradish peroxidase
Horseradish Peroxidase - metabolism
Lampreys
Marine
Motoneuron
Motor Neurons - physiology
Neural Pathways
Neurobiotin
Petromyzontidae
Rats
Spinal cord
Spinal Cord - cytology
Three-dimensional reconstruction
Turtles
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Numerous spinal motoneurons in mammals possess recurrent axon collaterals included in a feedback loop for controlling motoneuron activity. For nonmammalian vertebrates, the data concerning the existence of collaterals and their intraspinal branching are fragmentary and contradictory. We focused on axonal branching of motoneurons in lampreys, frogs, turtles and young rats, using light microscopic analysis of HRP- or neurobiotin-labeled motoneurons. In lampreys, only a restricted portion of spinal motoneurons, related to the dorsal fins, showed recurrent collaterals. In frogs, a great complexity and high total length of collateral branches as well as a great number of axon swellings were found. In turtles, axon collateralization of spinal motoneurons was much more restricted, and present in particular in lumbar motoneurons innervating proximal hindlimb muscles. Young rat spinal motoneurons have rather abundant recurrent axon collaterals. It is likely that the presence of axon collaterals from spinal motoneurons is related to the level of complexity of locomotion.
ISSN:0361-9230
1873-2747
DOI:10.1016/j.brainresbull.2004.08.008