Electroconvulsive therapy for depression in a Parkinson's disease patient with bilateral subthalamic nucleus deep brain stimulators

We report a patient with advanced Parkinson's disease (PD) who developed a recurrence of major depression with psychotic features after bilateral subthalamic nucleus (STN) deep brain stimulation (DBS) surgery. Electroconvulsive therapy (ECT) dramatically improved the depression without shifting...

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Bibliographic Details
Published in:Parkinsonism & related disorders 2005-09, Vol.11 (6), p.403-406
Main Authors: Chou, Kelvin L., Hurtig, Howard I., Jaggi, Jurg L., Baltuch, Gordon H., Pelchat, Rodney J., Weintraub, Daniel
Format: Article
Language:English
Subjects:
Antiparkinson Agents - therapeutic use
Antipsychotic Agents - therapeutic use
Deep Brain Stimulation
Depression
Depressive Disorder, Major - etiology
Depressive Disorder, Major - therapy
Dibenzothiazepines - therapeutic use
Electroconvulsive Therapy
Female
Humans
Levodopa - therapeutic use
Magnetic Resonance Imaging
Middle Aged
Parkinson Disease - complications
Parkinson Disease - therapy
Parkinson's disease
Quetiapine Fumarate
Subthalamic nucleus
Subthalamic Nucleus - physiology
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Summary:We report a patient with advanced Parkinson's disease (PD) who developed a recurrence of major depression with psychotic features after bilateral subthalamic nucleus (STN) deep brain stimulation (DBS) surgery. Electroconvulsive therapy (ECT) dramatically improved the depression without shifting electrode position or damaging the DBS hardware. This case suggests that ECT can be a safe and effective option for severe depression in PD patients treated with STN DBS.
ISSN:1353-8020
1873-5126
DOI:10.1016/j.parkreldis.2005.04.005