Image-Guided Radiosurgical Ablation of Intra- and Extra-Cranial Lesions

For decades since its introduction, stereotactic radiosurgery (SRS) was used only to treat intracranial lesions because intracranial targets could be immobilized and located relative to a rigid metal frame affixed to the patient's head. Lesions outside the head were generally not treated with S...

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Bibliographic Details
Published in:Technology in cancer research & treatment 2006-08, Vol.5 (4), p.421-428
Main Authors: Romanelli, Pantaleo, Schaal, David W., Adler, John R.
Format: Article
Language:English
Subjects:
Biological and medical sciences
Brain Neoplasms - surgery
Diseases of the nervous system
Equipment Design
Humans
Medical sciences
Neoplasms - surgery
Neuronavigation - instrumentation
Neuronavigation - methods
Radiosurgery - methods
Radiotherapy Planning, Computer-Assisted
Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
Robotics
Software
Spinal Cord Neoplasms - surgery
Surgery, Computer-Assisted - methods
Tumors
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Summary:For decades since its introduction, stereotactic radiosurgery (SRS) was used only to treat intracranial lesions because intracranial targets could be immobilized and located relative to a rigid metal frame affixed to the patient's head. Lesions outside the head were generally not treated with SRS because it is difficult to immobilize extracranial lesions and to attach stereotactic frames elsewhere on the body. Advances in computerized image guidance and robotics allowed the development of systems, such as the CyberKnife SRS System (Accuray, Inc, Sunnyvale, CA), that could target intracranial lesions without the stereotactic frame. Enhancements have resulted in a radiation delivery system that can accurately deliver high-dose, focal radiation to lesions in the spine, chest, and abdomen, even if they move during respiration. In this review we will describe the technical features of frameless SRS systems and briefly review their application to treating intracranial and extracranial lesions, focusing in particular on spinal lesions.
ISSN:1533-0346
1533-0338
DOI:10.1177/153303460600500410