Endoglin Structure and Function: DETERMINANTS OF ENDOGLIN PHOSPHORYLATION BY TRANSFORMING GROWTH FACTOR-β RECEPTORS

Determination of the functional relationship between the transforming growth factor-β (TGFβ) receptor proteins endoglin and ALK1 is essential to the understanding of the human vascular disease, hereditary hemorrhagic telangiectasia. TGFβ1 caused recruitment of ALK1 into a complex with endoglin in hu...

Full description

Saved in:
Bibliographic Details
Published in:The Journal of biological chemistry 2006-09, Vol.281 (35), p.25110-25123
Main Authors: Koleva, Rositsa I, Conley, Barbara A, Romero, Diana, Riley, Kristin S, Marto, Jarrod A, Lux, Andreas, Vary, Calvin P.H
Format: Article
Language:English
Subjects:
Activin Receptors, Type II - metabolism
Amino Acid Sequence
Antigens, CD - chemistry
Antigens, CD - physiology
Cells, Cultured
Cytosol - metabolism
Endoglin
Endothelium, Vascular - cytology
Humans
Molecular Sequence Data
Phosphorylation
Protein Structure, Tertiary
Receptors, Cell Surface - chemistry
Receptors, Cell Surface - physiology
Receptors, Transforming Growth Factor beta - metabolism
Sequence Homology, Amino Acid
Structure-Activity Relationship
Umbilical Veins - cytology
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!