Declining invasive pneumococcal disease in the U.S. elderly

In 2000, pneumococcal conjugate vaccine (PCV7) was recommended for young children. By 2002–2003, 48.6% had been fully immunized. Using Medicare administrative, we found that the rates of invasive pneumococcal disease (IPD) hospitalizations in the elderly in the 2000–2001, 2001–2002 and 2002–2003, we...

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Bibliographic Details
Published in:Vaccine 2005-12, Vol.23 (48), p.5641-5645
Main Authors: McBean, A. Marshall, Park, Young-Taek, Caldwell, Debra, Yu, Xinhua
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Applied microbiology
Bacteriology
Biological and medical sciences
Elderly
Fundamental and applied biological sciences. Psychology
Heptavalent Pneumococcal Conjugate Vaccine
Humans
Immunization
Immunization Programs
Incidence
Influenza
Invasive pneumococcal disease
Medicare
Meningitis
Meningococcal Vaccines - administration & dosage
Meningococcal Vaccines - therapeutic use
Microbiology
Miscellaneous
Outcome Assessment (Health Care)
Pneumococcal conjugate vaccine
Pneumococcal Infections - epidemiology
Pneumococcal Infections - ethnology
Pneumococcal Infections - prevention & control
Pneumococcal Vaccines - administration & dosage
Pneumococcal Vaccines - therapeutic use
Pneumonia
Streptococcus pneumoniae
United States - epidemiology
Vaccination - statistics & numerical data
Vaccines
Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)
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Summary:In 2000, pneumococcal conjugate vaccine (PCV7) was recommended for young children. By 2002–2003, 48.6% had been fully immunized. Using Medicare administrative, we found that the rates of invasive pneumococcal disease (IPD) hospitalizations in the elderly in the 2000–2001, 2001–2002 and 2002–2003, were 22.6, 30.2, and 40.6% lower, respectively, than during the baseline period, 1996–1997 through 1999–2000 (range 35.1/100,000 to 38.3/100,000). Pneumococcal polysaccharide vaccine (PPV23) has been recommended for the elderly, since 1989. PPV23 vaccination rates in the elderly increased by 25.2% during the baseline period but by
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2005.05.043