Evaluation of a primary care‐oriented brief counselling intervention for obesity with and without orlistat

. Objective.  There is a significant need for an obesity treatment model suitable for the primary care environment. We examined the effectiveness of a brief counselling intervention alone, in combination with orlistat, and drug‐alone in a 12‐month randomized‐clinical trial at a medical school obesit...

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Bibliographic Details
Published in:Journal of internal medicine 2006-10, Vol.260 (4), p.388-398
Main Authors: POSTON, W. S. C., HADDOCK, C. K., PINKSTON, M. M., PACE, P., REEVES, R. S., KARAKOC, N., JONES, P., FOREYT, J. P.
Format: Article
Language:English
Subjects:
Adult
Anti-Obesity Agents - therapeutic use
behavioural medicine
Biological and medical sciences
Cardiovascular Diseases - etiology
Counseling - methods
General aspects
Humans
Lactones - therapeutic use
Life Style
Medical sciences
Metabolic diseases
Middle Aged
Obesity
Obesity - drug therapy
Obesity - therapy
Patient Compliance
Patient Dropouts
primary care
Primary Health Care - methods
Risk Factors
Treatment Outcome
weight loss
Weight Loss - physiology
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Summary:. Objective.  There is a significant need for an obesity treatment model suitable for the primary care environment. We examined the effectiveness of a brief counselling intervention alone, in combination with orlistat, and drug‐alone in a 12‐month randomized‐clinical trial at a medical school obesity centre. Methods.  Participants (N = 250) with body mass index (BMI) ≥27 were randomized. Changes in body weight, lipids, blood pressure and serum glucose were examined. Drug adherence and attendance were also evaluated. Results.  Completers analysis was conducted on 136 participants with data at baseline, 6 and 12 months and intention‐to‐treat analyses (ITT) for the total sample. Amongst completers, participants in the drug only (P = 0.012) and drug + brief counselling (P = 0.001) groups lost more weight (mean ± SD: −3.8 ± 5.8 kg and −4.8 ± 4.4 kg, respectively) than participants in the brief counselling only group at 6 months (−1.7 ± 3.3 kg), but there were no significant group differences at 12 months. ITT model results were similar to completers at 6 months and remained significant at 12 months, but the weight losses were more modest (
ISSN:0954-6820
1365-2796
DOI:10.1111/j.1365-2796.2006.01702.x