Long Survival Following Bacterial Meningitis-Associated Brain Destruction

This report describes the brain autopsy of a boy who at age 4½ years experienced an episode of fulminant Haemophilus influenzae type b bacterial meningitis, resulting in massive brain destruction and the clinical signs of brain death. However, medical intervention maintained him for an additional tw...

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Bibliographic Details
Published in:Journal of child neurology 2006-07, Vol.21 (7), p.591-595
Main Authors: Repertinger, Susan, Fitzgibbons, William P., Omojola, Mathew F., Brumback, Roger A.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Bacteria
Brain Death - pathology
Child
Child, Preschool
Haemophilus influenzae
Haemophilus influenzae type b
Humans
Male
Meningitis, Haemophilus - pathology
Meningitis, Haemophilus - therapy
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Summary:This report describes the brain autopsy of a boy who at age 4½ years experienced an episode of fulminant Haemophilus influenzae type b bacterial meningitis, resulting in massive brain destruction and the clinical signs of brain death. However, medical intervention maintained him for an additional two decades. Subsequent autopsy revealed a calcified intracranial spherical structure weighing 750 g and consisting of a calcified shell containing grumous material and cystic spaces with no recognizable neural elements grossly or microscopically. This case represents an example of long survival of brain death with a living body. (J Child Neurol 2006;21:591—595; DOI 10.2310/7010.2006.00137).
ISSN:0883-0738
1708-8283
DOI:10.1177/08830738060210070401