Vaccines and immunotherapy for staphylococcal infections

Nosocomial or hospital-acquired infections are associated with prolonged hospitalizations and increased healthcare costs. Infections associated with surgical implants are becoming more difficult and more costly to manage, as they require repeated surgical procedures and a longer period of time to tr...

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Bibliographic Details
Published in:International journal of artificial organs 2005-11, Vol.28 (11), p.1157-1162
Main Author: Patti, J M
Format: Article
Language:English
Subjects:
Adhesins, Bacterial - immunology
Anti-Bacterial Agents - therapeutic use
Antibodies, Monoclonal - therapeutic use
Cross Infection - immunology
Cross Infection - therapy
Drug Resistance, Multiple, Bacterial
Humans
Immunotherapy
Staphylococcal Infections - immunology
Staphylococcal Infections - therapy
Staphylococcal Vaccines
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Summary:Nosocomial or hospital-acquired infections are associated with prolonged hospitalizations and increased healthcare costs. Infections associated with surgical implants are becoming more difficult and more costly to manage, as they require repeated surgical procedures and a longer period of time to treat patients. Continued advances in the use of medical devices, an increase in the number of immunocompromised patients, and a steady rise in the prevalence of antibiotic-resistant organisms has renewed interest in the development of novel therapies that can be used to prevent and treat nosocomial infections. This review provides an overview of bacterial adhesins and focuses on novel immunological therapies developed to treat staphylococcal infections.
ISSN:0391-3988
1724-6040
DOI:10.1177/039139880502801113