Void filling of tibia compression fracture zones using a novel resorbable nanocrystalline hydroxyapatite paste in combination with a hydroxyapatite ceramic core: first clinical results

It is a generally accepted standard surgical practice to fill-in the metaphyseal defect zones resulting from the reduction of tibia compression fractures. The development of various innovative bone substitutes is also currently on the increase. In our prospective study, we used Ostim, a novel resorb...

Full description

Saved in:
Bibliographic Details
Published in:Archives of orthopaedic and trauma surgery 2006-10, Vol.126 (8), p.533-540
Main Authors: Huber, Franz-Xaver, McArthur, Nicholas, Hillmeier, Joachim, Kock, Hans Jürgen, Baier, Martin, Diwo, Martin, Berger, Irina, Meeder, Peter Jürgen
Format: Article
Language:English
Subjects:
Absorbable Implants
Adult
Aged
Aged, 80 and over
Bone Cements - therapeutic use
Bone Substitutes - therapeutic use
Ceramics - therapeutic use
Female
Fractures
Fractures, Compression - diagnostic imaging
Fractures, Compression - surgery
Humans
Hydroxyapatite
Hydroxyapatites - therapeutic use
Male
Middle Aged
Nanoparticles - therapeutic use
Prospective Studies
Radiography
Range of Motion, Articular
Tibia - pathology
Tibial Fractures - diagnostic imaging
Tibial Fractures - surgery
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:It is a generally accepted standard surgical practice to fill-in the metaphyseal defect zones resulting from the reduction of tibia compression fractures. The development of various innovative bone substitutes is also currently on the increase. In our prospective study, we used Ostim, a novel resorbable nanocrystalline hydroxyapatite paste, together with Cerabone, a solid hydroxyapatite ceramic, in combination with angularly stable osteosynthesis to treat 24 tibia compression fractures. Types B2 and B3, as well as types C2 and C3 fractures, according to the AO classification, were included in the study. The mean total range of joint motion in terms of flexion and extension was improved from the immediate postoperative value of 79 +/- 14 degrees to 97 +/- 13 degrees at 6 weeks after surgery, to 109 +/- 16 degrees at 3 months, and finally to 118 +/- 17 degrees at 1 year. In three patients, a delayed wound healing was observed as a local complication. The use of the Ostim and Cerabone combination is an effective method in treating tibia compression fractures with large defect zones left after reduction.
ISSN:0936-8051
1434-3916
DOI:10.1007/s00402-006-0170-1