Cauda equina syndrome : Factors affecting long-term functional and sphincteric outcome

• Published in: Spine (Philadelphia, Pa. 1976) Pa. 1976), 2007-01, Vol.32 (2), p.207-216
• Main Authors: MCCARTHY, Michael J. H, AYLOTT, Caspar E. W, GREVITT, Michael P, HEGARTY, James
• Format: Article
• Language: English
• Subjects: Adult; Aged; Anal Canal - physiopathology; Biological and medical sciences; Cerebrospinal fluid. Meninges. Spinal cord; Cohort Studies; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases; Fecal Incontinence - etiology; Female; Follow-Up Studies; Humans; Intervertebral Disc Displacement - complications; Intestinal Diseases - etiology; Leg; Low Back Pain - complications; Lumbar Vertebrae; Male; Malformations of the nervous system; Medical sciences; Middle Aged; Muscle Weakness - etiology; Nervous system (semeiology, syndromes); Neurology; Orthopedic Procedures - adverse effects; Polyradiculopathy - complications; Polyradiculopathy - etiology; Polyradiculopathy - physiopathology; Polyradiculopathy - surgery; Prospective Studies; Recovery of Function; Retrospective Studies; Sacrum; Sciatica - complications; Sensation Disorders - etiology; Sexual Behavior; Time Factors; Urination Disorders - etiology
• ISSN: 0362-2436; 1528-1159
• DOI: 10.1097/01.brs.0000251750.20508.84

Retrospective cohort study with prospective clinical follow-up. To determine the factors that influence outcome after surgery for cauda equina syndrome (CES). CES is a rare but serious consequence of lumbar disc prolapse and can have devastating long-lasting neurologic consequences. The timing of surgical decompression remains controversial. Fifty-six patients with evidence of a sphincteric disturbance who underwent urgent surgery were identified and invited to follow-up. The outcome measures comprised history and examination and several validated self-assessment questionnaires. Forty-two patients (78%) attended with a mean follow-up of 60 months (range, 25-114 months). Mean age at onset was 41 years (range, 24-67 years) with 23 males and 19 females. Twenty-six patients were operated on within 48 hours of onset of sphincteric symptoms; 5 of these were within 24 hours. Acute onset of sphincteric symptoms and the time to operation did not influence the outcomes. Leg weakness at onset persisted in a significant number of patients at follow-up (P < 0.005). Urinary disturbance at presentation did not affect the outcomes. At follow-up, significantly more females had urinary incontinence (P < 0.005). Bowel dysfunction at presentation was associated with sexual problems at follow-up (P < 0.005). The 13 patients who failed their post operative trial without catheter had worse outcomes. The SF-36 scores at follow-up were reduced compared with age-matched controls in the population. The mean ODI was 29, Low Back Outcome Score 42, and VAS 4.5. The time elapsed from operation to follow-up was not found to influence the outcomes. In our series, the symptom duration before operation and the speed of onset do not affect the outcome more than 2 years after surgery. Based on the SF-36, ODI, and Low Back Outcome Scores, patients who have had CES do not return to a normal status.