Deficiency in Na,K-ATPase α Isoform Genes Alters Spatial Learning, Motor Activity, and Anxiety in Mice

Several disorders have been associated with mutations in Na,K-ATPase α isoforms (rapid-onset dystonia parkinsonism, familial hemiplegic migraine type-2), as well as reduction in Na,K-ATPase content (depression and Alzheimer's disease), thereby raising the issue of whether haploinsufficiency or...

Full description

Saved in:
Bibliographic Details
Published in:The Journal of neuroscience 2007-01, Vol.27 (3), p.616-626
Main Authors: Moseley, Amy E., Williams, Michael T., Schaefer, Tori L., Bohanan, Cynthia S., Neumann, Jon C., Behbehani, Michael M., Vorhees, Charles V., Lingrel, Jerry B
Format: Article
Language:English
Subjects:
Animals
Anxiety - enzymology
Anxiety - genetics
Isoenzymes - deficiency
Isoenzymes - genetics
Isoenzymes - physiology
Maze Learning - physiology
Mice
Mice, Knockout
Models, Animal
Motor Activity - physiology
Protein Subunits - biosynthesis
Protein Subunits - deficiency
Protein Subunits - genetics
Sodium-Potassium-Exchanging ATPase - deficiency
Sodium-Potassium-Exchanging ATPase - genetics
Sodium-Potassium-Exchanging ATPase - physiology
Spatial Behavior - physiology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!