Association of Atrial Fibrillation and Focal Neurologic Deficits With Impaired Cognitive Function in Hospitalized Patients ≥65 Years of Age

Atrial fibrillation (AF) is a risk factor for cerebrovascular diseases and can manifest as impaired cognitive function (ICF). ICF may be accompanied by various focal neurologic deficits (FNDs). This study evaluated cognitive function and the risk for ICF in patients aged ≥65 years hospitalized for a...

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Bibliographic Details
Published in:The American journal of cardiology 2006-11, Vol.98 (9), p.1238-1241
Main Authors: Jozwiak, Andrzej, Guzik, Przemyslaw, Mathew, Anup, Wykretowicz, Andrzej, Wysocki, Henryk
Format: Article
Language:English
Subjects:
Age Factors
Aged
Aged, 80 and over
Analysis of Variance
Atrial Fibrillation - complications
Atrial Fibrillation - physiopathology
Biological and medical sciences
Cardiac dysrhythmias
Cardiology. Vascular system
Cardiovascular disease
Cognition & reasoning
Cognition Disorders - etiology
Cognition Disorders - physiopathology
Female
Heart
Hospitalization
Humans
Inpatients
Male
Medical sciences
Nervous System Diseases - complications
Nervous System Diseases - etiology
Nervous System Diseases - physiopathology
Neurology
Neuropsychological Tests
Older people
Psychomotor Performance
Retrospective Studies
Risk Factors
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Summary:Atrial fibrillation (AF) is a risk factor for cerebrovascular diseases and can manifest as impaired cognitive function (ICF). ICF may be accompanied by various focal neurologic deficits (FNDs). This study evaluated cognitive function and the risk for ICF in patients aged ≥65 years hospitalized for any reason and grouped according to the presence of AF and/or FNDs. Data on 2,314 conscious patients aged ≥65 years (1,506 women) were analyzed. Physical examination, electrocardiography at rest, and the Mini-Mental State Examination were performed at admission. The median Mini-Mental State Examination score was 25 in patients without AF or FNDs (63.4%), 23 in those with AF alone (23.6%), 21 in those with FNDs alone (8.9%), and 18 in those with AF and FNDs (4.1%). On multivariate logistic regression (adjusted for age and gender), the risk for ICF was increased in patients with AF alone (p
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2006.05.058