Primary and Secondary Heart Tumours in Dogs and Cats

• Published in: Journal of comparative pathology 2007, Vol.136 (1), p.18-26
• Main Authors: Aupperle, H., März, I., Ellenberger, C., Buschatz, S., Reischauer, A., Schoon, H.-A.
• Format: Article
• Language: English
• Subjects: Animals; benign tumors; cardiac tumors; cardiac tumours; cat; Cat Diseases - pathology; Cats; dog; Dog Diseases - pathology; Dogs; echocardiography; heart; Heart Neoplasms - pathology; Heart Neoplasms - secondary; Heart Neoplasms - veterinary; heart tumors; Hemangiosarcoma - pathology; Hemangiosarcoma - secondary; Hemangiosarcoma - veterinary; histopathology; immunohistochemistry; Lymphoma, B-Cell - pathology; Lymphoma, B-Cell - veterinary; malignant tumors; metastasis; Neoplasm Metastasis; neoplasms; Neurofibrosarcoma - pathology; Neurofibrosarcoma - secondary; Neurofibrosarcoma - veterinary; Paraganglioma, Extra-Adrenal - pathology; Paraganglioma, Extra-Adrenal - secondary; Paraganglioma, Extra-Adrenal - veterinary; pericardium; primary neoplasms; secondary neoplasms; tumour
• ISSN: 0021-9975; 1532-3129
• DOI: 10.1016/j.jcpa.2006.10.002

Primary and secondary neoplasms of the canine and feline heart are uncommon. During a 2-year period, 83 dogs suffering from primary cardiac ( n=11), extracardiac benign ( n=6) or malignant ( n=66) tumours and 30 cats with primary cardiac ( n=1) or extracardiac ( n=29) malignant tumours were examined. Echocardiography revealed four cases of primary cardiac neoplasms in dogs, but secondary heart tumours were not detected. After necropsy, tissue samples from the heart and tumours were examined histologically and immunohistochemically. In dogs, primary neoplasms included seven haemangiosarcomas, two chemodectomas, one rhabdomyosarcoma, and one neurofibrosarcoma. In 24 of 66 dogs examined, metastases of extracardiac neoplasms were found in the heart (15 carcinomas, six malignant lymphomas, three haemangiosarcomas). In cats, one case of primary haemangiosarcoma of the pericardium and five cases of secondary cardiac tumours (two malignant lymphomas, three carcinomas) occurred. Cardiac neoplasms in cats were not identified clinically but were detected by detailed gross sectioning of the heart ( n=2) or histopathological examinations ( n=3). This study showed an unexpectedly high number (36%) of dogs with cardiac metastases.