Exercise-Induced Hypertension, Endothelial Dysfunction, and Coronary Artery Disease in a Marathon Runner

Aerobic activity performed on a regular basis is 1 of several lifestyle recommendations endorsed to reduce risk of coronary disease. However, 1 potential concern of arduous aerobic activity is exercise-induced hypertension. This is the first case to our knowledge, of accelerated coronary calcificati...

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Bibliographic Details
Published in:The American journal of cardiology 2007-03, Vol.99 (5), p.743-744
Main Authors: Goel, Radha, MD, Majeed, Farhan, MD, Vogel, Robert, MD, Corretti, Mary C., MD, Weir, Matthew, MD, Mangano, Charles, RDMS, White, Charles, MD, Plotnick, Gary D., MD, Miller, Michael, MD
Format: Article
Language:English
Subjects:
Arterial hypertension. Arterial hypotension
Athletes
Biological and medical sciences
Blood and lymphatic vessels
Cardiology
Cardiology. Vascular system
Cardiovascular
Cardiovascular disease
Coronary Artery Disease - etiology
Coronary Artery Disease - physiopathology
Coronary Artery Disease - prevention & control
Coronary heart disease
Endothelium, Vascular - physiopathology
Exercise
Heart
Humans
Hypertension
Hypertension - etiology
Hypertension - physiopathology
Hypertension - prevention & control
Male
Marathons
Medical sciences
Middle Aged
Running - physiology
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Summary:Aerobic activity performed on a regular basis is 1 of several lifestyle recommendations endorsed to reduce risk of coronary disease. However, 1 potential concern of arduous aerobic activity is exercise-induced hypertension. This is the first case to our knowledge, of accelerated coronary calcification in an otherwise asymptomatic middle-aged male marathon runner devoid of traditional cardiovascular risk factors. As a consequence of exercise-induced hypertension and associated oxidative stress, improvement of endothelial dysfunction occurred after antioxidant supplementation. In conclusion, vigorous aerobic activity in susceptible individuals may promote oxidative stress and coronary atherosclerosis.
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2006.09.127