Impact of acute exercise on bone turnover and growth hormone/insulin-like growth factor axis in boys

The aim of this study was to investigate the response of N-terminal propeptide of type I procollagen, crosslinked telopeptide of type I collagen and the growth hormone/insulin-like growth factor-I axis to acute aerobic exercise in boys at different pubertal stages The subjects were 60 healthy boys (...

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Bibliographic Details
Published in:Journal of sports medicine and physical fitness 2008-06, Vol.48 (2), p.266-271
Main Authors: POMERANTS, T, TILLMANN, V, KARELSON, K, JÜRIMÄE, J, JÜRIMÄE, T
Format: Article
Language:English
Subjects:
Adolescent
Biological and medical sciences
Body Composition
Body Height
Bone density
Bone Remodeling - physiology
Bones
Child
Ergometry
Exercise
Fundamental and applied biological sciences. Psychology
Human Growth Hormone - blood
Humans
Male
Males
Measurement Techniques
Metabolism
Physical Education
Puberty
Puberty - physiology
Scientific Concepts
Somatomedins - analysis
Studies
Testosterone - blood
Vertebrates: body movement. Posture. Locomotion. Flight. Swimming. Physical exercise. Rest. Sports
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Summary:The aim of this study was to investigate the response of N-terminal propeptide of type I procollagen, crosslinked telopeptide of type I collagen and the growth hormone/insulin-like growth factor-I axis to acute aerobic exercise in boys at different pubertal stages The subjects were 60 healthy boys (group I - Tanner stage 1, N=20; group II - Tanner stages 2 and 3, N=20; group III - Tanner stages 4 and 5, N=20) who exercised 30 minutes at constant load on cycle ergometer at the level of ~95% of their individual ventilatory threshold. Venous blood samples were obtained before, immediately after and after 30 minutes of recovery for the measurement of serum testosterone, growth hormone (GH), insulin-like-growth factor-I, insulin-like-growth factor binding protein-3, N-terminal propeptide of type I procollagen (PINP) and crosslinked telopeptide of type I collagen. Acute exercise did not affect significantly serum testosterone, insulin-like-growth factor-I, insulin-like-growth factor binding protein-3 or bone turnover markers concentrations in any of study groups. The rise in growth hormone concentration during exercise was highest in group III (62.3+/-41.7 mU/L vs 15.5+/-11.4 in group I and 41.8+/-20.0 in group II). The increment in serum growth hormone level during exercise was positively correlated (r=0.64; P
ISSN:0022-4707
1827-1928