Abdominal sacrocolpopexy: anatomic outcomes and complications with Pelvicol, autologous and synthetic graft materials

Objective The purpose of this study was to compare anatomic outcomes and graft-related complications (GRCs) for abdominal sacrocolpopexy (ASC) with Pelvicol (CR BARD, Murray Hill, NJ), autologous fascia, and synthetic grafts. Study Design This is a retrospective cohort study of ASC from 2001-2005. W...

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Bibliographic Details
Published in:American journal of obstetrics and gynecology 2008-05, Vol.198 (5), p.557.e1-557.e5
Main Authors: Quiroz, Lieschen H., MD, Gutman, Robert E., MD, Shippey, Stuart, MD, Cundiff, Geoffery W., MD, Sanses, Tatiana, MD, Blomquist, Joan L., MD, Handa, Victoria L., MD
Format: Article
Language:English
Subjects:
abdominal sacrocolpopexy
Adult
Aged
Biological and medical sciences
Fascia - transplantation
Female
graft material
Gynecologic Surgical Procedures - methods
Gynecology. Andrology. Obstetrics
Humans
Medical sciences
Middle Aged
Obstetrics and Gynecology
prolapse
Prostheses and Implants
Reoperation
Retrospective Studies
Sacrum - surgery
Surgical Mesh
Suture Techniques
Treatment Outcome
Uterine Prolapse - surgery
Vagina - surgery
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Summary:Objective The purpose of this study was to compare anatomic outcomes and graft-related complications (GRCs) for abdominal sacrocolpopexy (ASC) with Pelvicol (CR BARD, Murray Hill, NJ), autologous fascia, and synthetic grafts. Study Design This is a retrospective cohort study of ASC from 2001-2005. We reviewed anatomic outcomes and GRCs. Apical failure was defined as >stage 0. Results Of 259 ASC procedures, Pelvicol was used in 102 procedures (39%); synthetic mesh in 134 procedures (52%), and autologous fascia in 23 procedures (9%). Mean postoperative follow up was 1.1 years. Apical failure by graft group were Pelvicol 10 (11%), synthetics 1 (1%), and autologous 1 (7%; P = .011). All 7 reoperations for apical prolapse were in the Pelvicol group. GRCs occurred in 16% of the cases, with a higher proportion of erosions in the Pelvicol group (11% vs 3% and 4%; P = .045). Reoperations as a result of GRC were similar between groups. Conclusion ASC is more likely to fail with Pelvicol than with synthetic or autologous grafts. The use of Pelvicol did not reduce graft-related complications in this population.
ISSN:0002-9378
1097-6868
DOI:10.1016/j.ajog.2008.01.050