Acute Colitis Associated With Dengue Fever in a Renal Transplant Recipient

Abstract Dengue fever is a significant health problem for international travelers to all endemic area. Dengue fever is characterized by a sudden onset of fever, headache, rash, myalgia, and joint pain. Infection with the dengue virus is detrimental to a immunosuppressed renal transplant patients. He...

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Bibliographic Details
Published in:Transplantation proceedings 2008-09, Vol.40 (7), p.2431-2432
Main Authors: Park, S.B, Ryu, S.Y, Jin, K.B, Hwang, E.A, Han, S.Y, Kim, H.T, Cho, W.H, Kwak, J.H, Ahn, K.S, Kim, H.C
Format: Article
Language:English
Subjects:
Acute Disease
Adult
Arboviroses
Biological and medical sciences
Colitis - etiology
Dengue - complications
Dengue fevers
Diarrhea - etiology
Female
Fundamental and applied biological sciences. Psychology
Fundamental immunology
Human viral diseases
Humans
Infectious diseases
Kidney Failure, Chronic - surgery
Kidney Transplantation - adverse effects
Medical sciences
Postoperative Complications - virology
Surgery
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Tissue, organ and graft immunology
Travel
Tropical viral diseases
Viral diseases
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Summary:Abstract Dengue fever is a significant health problem for international travelers to all endemic area. Dengue fever is characterized by a sudden onset of fever, headache, rash, myalgia, and joint pain. Infection with the dengue virus is detrimental to a immunosuppressed renal transplant patients. Herein we report a 29-year-old woman living-related renal transplant recipient returning from Southeast Asia with dengue fever presenting as acute colitis. The patient traveled to Southeast Asia for 1 week. She developed watery diarrhea in the second week after the onset of symptoms of dengue fever. Laboratory findings were leukopenia, thrombocytopenia, and elevated serum transaminase levels. Sigmoidoscopic features showed nonspecific acute colitis. She improved after 10 days of hospitalization with intensive supportive care and continuous tacrolimus monotherapy. Altered clinical symptoms are manifested in immunologically naïve adults. Manifestation of unusual symptoms does not exclude dengue virus infection in renal transplant recipients.
ISSN:0041-1345
1873-2623
DOI:10.1016/j.transproceed.2008.07.037