Malignant Glomus Tumors

Objectives/Hypothesis: To ascertain the incidence of malignancy in a large glomus and skull base series and to compare the clinical course of such patients with those who do not have malignant skull base lesions. Study Design: Retrospective review of all skull base surgery cases treated at the Otolo...

Full description

Saved in:
Bibliographic Details
Published in:The Laryngoscope 1999-01, Vol.109 (1), p.30-34
Main Authors: Manolidis, Spiros, Shohet, Jack A., Jackson, C. Gary, Glasscock III, Michael E.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Biological and medical sciences
Child
Female
Glomus Jugulare Tumor - surgery
Glomus Tumor - mortality
Glomus Tumor - surgery
Humans
Male
Medical sciences
Middle Aged
Otorhinolaryngology (head neck, general aspects and miscellaneous)
Otorhinolaryngology. Stomatology
Retrospective Studies
Skull Neoplasms - mortality
Skull Neoplasms - surgery
Temporal Bone
Tumors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Objectives/Hypothesis: To ascertain the incidence of malignancy in a large glomus and skull base series and to compare the clinical course of such patients with those who do not have malignant skull base lesions. Study Design: Retrospective review of all skull base surgery cases treated at the Otology Group between 1970 and 1995. Results: In a series of 175 jugulotympanic glomus tumors, 9 cases (5.1%) were identified. The surgery required for their extirpation is more extensive than nonmalignant glomus tumors. Attendant deficits and mortality from these procedures are accordingly greater. Five‐year survival in this limited population was 72%. Prolonged periods of survival are possible with distant metastases. Conclusions: This rate of malignancy should advocate against a watchful, waiting approach. Radiation therapy is not advocated as a primary modality for this type of tumor, as it may lead to recurrence/persistence with either subsequent malignant degeneration and metastases or local recurrence.
ISSN:0023-852X
1531-4995
DOI:10.1097/00005537-199901000-00007