Loading…
The use of fluconazole as a local irrigant for nephrostomy tubes
Few data exist concerning the combined use of fluconazole systemically and as an irrigant for nephrostomy tubes in a patient with renal candidiasis. The patient described here presented with renal fungal balls obstructing the drainage of urine from her nephrostomy tubes. Twelve months after chemorad...
Saved in:
| Published in: | Military medicine 1999-03, Vol.164 (3), p.239-241 |
|---|---|
| Main Authors: | , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c393t-aac97500e805e349f0efd472a944b710ab709cd2656dd9c47e79b436ceb8f4023 |
|---|---|
| cites | |
| container_end_page | 241 |
| container_issue | 3 |
| container_start_page | 239 |
| container_title | Military medicine |
| container_volume | 164 |
| creator | CLARK, M. A GAUNT, T CZACHOR, J. S |
| description | Few data exist concerning the combined use of fluconazole systemically and as an irrigant for nephrostomy tubes in a patient with renal candidiasis. The patient described here presented with renal fungal balls obstructing the drainage of urine from her nephrostomy tubes.
Twelve months after chemoradiation for a stage IIB squamous cell carcinoma of the uterine cervix, a 35-year-old woman presented with renal obstruction necessitating insertion of ureteral stents. After 6 months of chemotherapy, the patient developed uremia. After nephrostomy tubes were placed, renal candidiasis was noted, and fluconazole was begun systemically. When the renal candidiasis failed to clear, nephrostomy tube irrigations were begun.
Fourteen days of therapy with fluconazole resulted in the resolution of the uremia. The patient died 6 months later with her nephrostomy tubes in situ and without evidence of candidiasis in her urinary tract.
The patient described was successfully treated without having to remove her nephrostomy tubes. Two other authors have reported the successful use of fluconazole irrigation to treat candidiasis in nephrostomy tubes that was unresponsive to systemic fluconazole. Before the appearance of these reports, the best results were obtained with removal of the catheter in renal candidiasis. |
| doi_str_mv | 10.1093/milmed/164.3.239 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_69650654</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>40000133</sourcerecordid><originalsourceid>FETCH-LOGICAL-c393t-aac97500e805e349f0efd472a944b710ab709cd2656dd9c47e79b436ceb8f4023</originalsourceid><addsrcrecordid>eNpdkE1LxDAQhoMouq7ePUkQ8dZ10nw1N2XxCxa8KHgLaZq4lbZZk_agv97ILgie5jDP-zLzIHRGYEFA0eu-7XrXXBPBFnRRUrWHZkRRKAShb_toBlCKgoHkR-g4pQ8AwlRFDtERAVCEQzlDNy9rh6fkcPDYd5MNg_kOncMmYYO7YE2H2xjbdzOM2IeIB7dZx5DG0H_hcapdOkEH3nTJne7mHL3e370sH4vV88PT8nZVWKroWBhjleQArgLuKFMenG-YLI1irJYETC1B2aYUXDSNskw6qWpGhXV15RmUdI6utr2bGD4nl0bdt8m6rjODC1PSQgkOgrMMXvwDP8IUh3ybLokETiTnGYItZPMzKTqvN7HtTfzSBPSvWr1Vq7NaTXVWmyPnu96p_t38BbYuM3C5A0zK3nw0g23THydJVVFCfwBIlIFy</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>217051755</pqid></control><display><type>article</type><title>The use of fluconazole as a local irrigant for nephrostomy tubes</title><source>Oxford Journals Online</source><creator>CLARK, M. A ; GAUNT, T ; CZACHOR, J. S</creator><creatorcontrib>CLARK, M. A ; GAUNT, T ; CZACHOR, J. S</creatorcontrib><description>Few data exist concerning the combined use of fluconazole systemically and as an irrigant for nephrostomy tubes in a patient with renal candidiasis. The patient described here presented with renal fungal balls obstructing the drainage of urine from her nephrostomy tubes.
Twelve months after chemoradiation for a stage IIB squamous cell carcinoma of the uterine cervix, a 35-year-old woman presented with renal obstruction necessitating insertion of ureteral stents. After 6 months of chemotherapy, the patient developed uremia. After nephrostomy tubes were placed, renal candidiasis was noted, and fluconazole was begun systemically. When the renal candidiasis failed to clear, nephrostomy tube irrigations were begun.
Fourteen days of therapy with fluconazole resulted in the resolution of the uremia. The patient died 6 months later with her nephrostomy tubes in situ and without evidence of candidiasis in her urinary tract.
The patient described was successfully treated without having to remove her nephrostomy tubes. Two other authors have reported the successful use of fluconazole irrigation to treat candidiasis in nephrostomy tubes that was unresponsive to systemic fluconazole. Before the appearance of these reports, the best results were obtained with removal of the catheter in renal candidiasis.</description><identifier>ISSN: 0026-4075</identifier><identifier>EISSN: 1930-613X</identifier><identifier>DOI: 10.1093/milmed/164.3.239</identifier><identifier>PMID: 10091502</identifier><identifier>CODEN: MMEDA9</identifier><language>eng</language><publisher>Bethesda, MD: Association of Military Surgeons</publisher><subject>Adult ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; Antifungal agents ; Antifungal Agents - therapeutic use ; Biological and medical sciences ; Candidiasis - drug therapy ; Candidiasis - etiology ; Carcinoma, Squamous Cell - drug therapy ; Catheters ; Cervix ; Chemotherapy ; Creatinine ; Fatal Outcome ; Female ; Fluconazole - therapeutic use ; Fungal infections ; Fungemia - drug therapy ; Fungemia - etiology ; Humans ; Kidney Diseases - drug therapy ; Kidney Diseases - etiology ; Medical sciences ; Nephrostomy, Percutaneous ; Patients ; Pharmacology. Drug treatments ; Silicones ; Stents ; Therapeutic Irrigation - methods ; Uremia ; Urine ; Urogenital system ; Uterine Cervical Neoplasms - drug therapy ; Vagina</subject><ispartof>Military medicine, 1999-03, Vol.164 (3), p.239-241</ispartof><rights>1999 INIST-CNRS</rights><rights>Copyright Association of Military Surgeons of the U.S. Mar 1999</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c393t-aac97500e805e349f0efd472a944b710ab709cd2656dd9c47e79b436ceb8f4023</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1718831$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10091502$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>CLARK, M. A</creatorcontrib><creatorcontrib>GAUNT, T</creatorcontrib><creatorcontrib>CZACHOR, J. S</creatorcontrib><title>The use of fluconazole as a local irrigant for nephrostomy tubes</title><title>Military medicine</title><addtitle>Mil Med</addtitle><description>Few data exist concerning the combined use of fluconazole systemically and as an irrigant for nephrostomy tubes in a patient with renal candidiasis. The patient described here presented with renal fungal balls obstructing the drainage of urine from her nephrostomy tubes.
Twelve months after chemoradiation for a stage IIB squamous cell carcinoma of the uterine cervix, a 35-year-old woman presented with renal obstruction necessitating insertion of ureteral stents. After 6 months of chemotherapy, the patient developed uremia. After nephrostomy tubes were placed, renal candidiasis was noted, and fluconazole was begun systemically. When the renal candidiasis failed to clear, nephrostomy tube irrigations were begun.
Fourteen days of therapy with fluconazole resulted in the resolution of the uremia. The patient died 6 months later with her nephrostomy tubes in situ and without evidence of candidiasis in her urinary tract.
The patient described was successfully treated without having to remove her nephrostomy tubes. Two other authors have reported the successful use of fluconazole irrigation to treat candidiasis in nephrostomy tubes that was unresponsive to systemic fluconazole. Before the appearance of these reports, the best results were obtained with removal of the catheter in renal candidiasis.</description><subject>Adult</subject><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents</subject><subject>Antifungal agents</subject><subject>Antifungal Agents - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Candidiasis - drug therapy</subject><subject>Candidiasis - etiology</subject><subject>Carcinoma, Squamous Cell - drug therapy</subject><subject>Catheters</subject><subject>Cervix</subject><subject>Chemotherapy</subject><subject>Creatinine</subject><subject>Fatal Outcome</subject><subject>Female</subject><subject>Fluconazole - therapeutic use</subject><subject>Fungal infections</subject><subject>Fungemia - drug therapy</subject><subject>Fungemia - etiology</subject><subject>Humans</subject><subject>Kidney Diseases - drug therapy</subject><subject>Kidney Diseases - etiology</subject><subject>Medical sciences</subject><subject>Nephrostomy, Percutaneous</subject><subject>Patients</subject><subject>Pharmacology. Drug treatments</subject><subject>Silicones</subject><subject>Stents</subject><subject>Therapeutic Irrigation - methods</subject><subject>Uremia</subject><subject>Urine</subject><subject>Urogenital system</subject><subject>Uterine Cervical Neoplasms - drug therapy</subject><subject>Vagina</subject><issn>0026-4075</issn><issn>1930-613X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><recordid>eNpdkE1LxDAQhoMouq7ePUkQ8dZ10nw1N2XxCxa8KHgLaZq4lbZZk_agv97ILgie5jDP-zLzIHRGYEFA0eu-7XrXXBPBFnRRUrWHZkRRKAShb_toBlCKgoHkR-g4pQ8AwlRFDtERAVCEQzlDNy9rh6fkcPDYd5MNg_kOncMmYYO7YE2H2xjbdzOM2IeIB7dZx5DG0H_hcapdOkEH3nTJne7mHL3e370sH4vV88PT8nZVWKroWBhjleQArgLuKFMenG-YLI1irJYETC1B2aYUXDSNskw6qWpGhXV15RmUdI6utr2bGD4nl0bdt8m6rjODC1PSQgkOgrMMXvwDP8IUh3ybLokETiTnGYItZPMzKTqvN7HtTfzSBPSvWr1Vq7NaTXVWmyPnu96p_t38BbYuM3C5A0zK3nw0g23THydJVVFCfwBIlIFy</recordid><startdate>19990301</startdate><enddate>19990301</enddate><creator>CLARK, M. A</creator><creator>GAUNT, T</creator><creator>CZACHOR, J. S</creator><general>Association of Military Surgeons</general><general>Oxford University Press</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>4T-</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88F</scope><scope>88G</scope><scope>88I</scope><scope>8AF</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>M1Q</scope><scope>M2M</scope><scope>M2P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>S0X</scope><scope>7X8</scope></search><sort><creationdate>19990301</creationdate><title>The use of fluconazole as a local irrigant for nephrostomy tubes</title><author>CLARK, M. A ; GAUNT, T ; CZACHOR, J. S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c393t-aac97500e805e349f0efd472a944b710ab709cd2656dd9c47e79b436ceb8f4023</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1999</creationdate><topic>Adult</topic><topic>Antibiotics. Antiinfectious agents. Antiparasitic agents</topic><topic>Antifungal agents</topic><topic>Antifungal Agents - therapeutic use</topic><topic>Biological and medical sciences</topic><topic>Candidiasis - drug therapy</topic><topic>Candidiasis - etiology</topic><topic>Carcinoma, Squamous Cell - drug therapy</topic><topic>Catheters</topic><topic>Cervix</topic><topic>Chemotherapy</topic><topic>Creatinine</topic><topic>Fatal Outcome</topic><topic>Female</topic><topic>Fluconazole - therapeutic use</topic><topic>Fungal infections</topic><topic>Fungemia - drug therapy</topic><topic>Fungemia - etiology</topic><topic>Humans</topic><topic>Kidney Diseases - drug therapy</topic><topic>Kidney Diseases - etiology</topic><topic>Medical sciences</topic><topic>Nephrostomy, Percutaneous</topic><topic>Patients</topic><topic>Pharmacology. Drug treatments</topic><topic>Silicones</topic><topic>Stents</topic><topic>Therapeutic Irrigation - methods</topic><topic>Uremia</topic><topic>Urine</topic><topic>Urogenital system</topic><topic>Uterine Cervical Neoplasms - drug therapy</topic><topic>Vagina</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>CLARK, M. A</creatorcontrib><creatorcontrib>GAUNT, T</creatorcontrib><creatorcontrib>CZACHOR, J. S</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Docstoc</collection><collection>Nursing & Allied Health Database</collection><collection>ProQuest_Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Military Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>eLibrary</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Family Health Database (Proquest)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest Military Collection</collection><collection>Psychology Database</collection><collection>ProQuest Science Journals</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>SIRS Editorial</collection><collection>MEDLINE - Academic</collection><jtitle>Military medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>CLARK, M. A</au><au>GAUNT, T</au><au>CZACHOR, J. S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The use of fluconazole as a local irrigant for nephrostomy tubes</atitle><jtitle>Military medicine</jtitle><addtitle>Mil Med</addtitle><date>1999-03-01</date><risdate>1999</risdate><volume>164</volume><issue>3</issue><spage>239</spage><epage>241</epage><pages>239-241</pages><issn>0026-4075</issn><eissn>1930-613X</eissn><coden>MMEDA9</coden><abstract>Few data exist concerning the combined use of fluconazole systemically and as an irrigant for nephrostomy tubes in a patient with renal candidiasis. The patient described here presented with renal fungal balls obstructing the drainage of urine from her nephrostomy tubes.
Twelve months after chemoradiation for a stage IIB squamous cell carcinoma of the uterine cervix, a 35-year-old woman presented with renal obstruction necessitating insertion of ureteral stents. After 6 months of chemotherapy, the patient developed uremia. After nephrostomy tubes were placed, renal candidiasis was noted, and fluconazole was begun systemically. When the renal candidiasis failed to clear, nephrostomy tube irrigations were begun.
Fourteen days of therapy with fluconazole resulted in the resolution of the uremia. The patient died 6 months later with her nephrostomy tubes in situ and without evidence of candidiasis in her urinary tract.
The patient described was successfully treated without having to remove her nephrostomy tubes. Two other authors have reported the successful use of fluconazole irrigation to treat candidiasis in nephrostomy tubes that was unresponsive to systemic fluconazole. Before the appearance of these reports, the best results were obtained with removal of the catheter in renal candidiasis.</abstract><cop>Bethesda, MD</cop><pub>Association of Military Surgeons</pub><pmid>10091502</pmid><doi>10.1093/milmed/164.3.239</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0026-4075 |
| ispartof | Military medicine, 1999-03, Vol.164 (3), p.239-241 |
| issn | 0026-4075 1930-613X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_69650654 |
| source | Oxford Journals Online |
| subjects | Adult Antibiotics. Antiinfectious agents. Antiparasitic agents Antifungal agents Antifungal Agents - therapeutic use Biological and medical sciences Candidiasis - drug therapy Candidiasis - etiology Carcinoma, Squamous Cell - drug therapy Catheters Cervix Chemotherapy Creatinine Fatal Outcome Female Fluconazole - therapeutic use Fungal infections Fungemia - drug therapy Fungemia - etiology Humans Kidney Diseases - drug therapy Kidney Diseases - etiology Medical sciences Nephrostomy, Percutaneous Patients Pharmacology. Drug treatments Silicones Stents Therapeutic Irrigation - methods Uremia Urine Urogenital system Uterine Cervical Neoplasms - drug therapy Vagina |
| title | The use of fluconazole as a local irrigant for nephrostomy tubes |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-01T09%3A43%3A20IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20use%20of%20fluconazole%20as%20a%20local%20irrigant%20for%20nephrostomy%20tubes&rft.jtitle=Military%20medicine&rft.au=CLARK,%20M.%20A&rft.date=1999-03-01&rft.volume=164&rft.issue=3&rft.spage=239&rft.epage=241&rft.pages=239-241&rft.issn=0026-4075&rft.eissn=1930-613X&rft.coden=MMEDA9&rft_id=info:doi/10.1093/milmed/164.3.239&rft_dat=%3Cproquest_cross%3E40000133%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c393t-aac97500e805e349f0efd472a944b710ab709cd2656dd9c47e79b436ceb8f4023%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=217051755&rft_id=info:pmid/10091502&rfr_iscdi=true |