Synchronous appearance of keratoacanthomas in burn scar and skin graft donor site shortly after injury

Skin malignancies can originate in burn scars (Marjolin’s ulcer). The most common is squamous cell carcinoma, usually appearing years after injury. Split-thickness skin graft donor sites as a source of malignant transformation are far less frequent and demonstrate a shorter interval between surgery...

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Bibliographic Details
Published in:Journal of the American Academy of Dermatology 1999-05, Vol.40 (5), p.870-871
Main Authors: Tamir, Gabriel, Morgenstern, Sara, Ben-Amitay, Dan, Okon, Eli, Hauben, Daniel J
Format: Article
Language:English
Subjects:
Biological and medical sciences
Burns - complications
Cicatrix - complications
Dermatology
Dermis - pathology
Eosinophils - pathology
Epidermis - pathology
Fibrosis
Humans
Keratins - analysis
Keratoacanthoma - etiology
Keratoacanthoma - pathology
Lymphocytes - pathology
Male
Medical sciences
Middle Aged
Skin Transplantation - adverse effects
Tumors of the skin and soft tissue. Premalignant lesions
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Summary:Skin malignancies can originate in burn scars (Marjolin’s ulcer). The most common is squamous cell carcinoma, usually appearing years after injury. Split-thickness skin graft donor sites as a source of malignant transformation are far less frequent and demonstrate a shorter interval between surgery and tumor onset. Keratoacanthomas have rarely been reported to arise in such scars. We describe the simultaneous occurrence of keratoacanthomas on a spontaneously healed second-degree burn on the flank and in the scar of a skin graft donor site on the thigh, 4 months after a 40% total body surface area burn. (J Am Acad Dermatol 1999;40:870-1.)
ISSN:0190-9622
1097-6787
DOI:10.1053/jd.1999.v40.a94419