Creatine supplementation differentially affects maximal isometric strength and time to fatigue in large and small muscle groups

Ten physically active, untrained, college-aged males (26.4 +/- 5.8 years old) received creatine (CR, 5 g creatine monohydrate + 3 g dextrose) and placebo (PLA, 7 g dextrose) supplementation four times per day for 5 days in a double-blind, randomized, balanced, crossover design. Performance was asses...

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Bibliographic Details
Published in:International journal of sport nutrition 1999-06, Vol.9 (2), p.136-145
Main Authors: Urbanski, R.L, Loy, S.F, Vincent, W.J, Yaspelkis, B.B. III
Format: Article
Language:English
Subjects:
Adult
athletic performance
creatine
Creatine - administration & dosage
Cross-Over Studies
Dietary Supplements
Double-Blind Method
Hand Strength
Humans
Isometric Contraction - drug effects
Male
men
Muscle Fatigue - drug effects
Muscle, Skeletal - drug effects
Muscle, Skeletal - physiology
phosphocreatine
Placebos
skeletal muscle
Time Factors
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Summary:Ten physically active, untrained, college-aged males (26.4 +/- 5.8 years old) received creatine (CR, 5 g creatine monohydrate + 3 g dextrose) and placebo (PLA, 7 g dextrose) supplementation four times per day for 5 days in a double-blind, randomized, balanced, crossover design. Performance was assessed during maximal and three repeated submaximal bouts of isometric knee extension and handgrip exercise. CR supplementation significantly increased (p < .05) maximal isometric strength during knee extension but not during handgrip exercise. CR supplementation increased time to fatigue during each of the three bouts of submaximal knee extension and handgrip exercise when compared to the PLA trials. These findings suggest that CR supplementation can increase maximal strength and time to fatigue during isometric exercise. However, the improvements in maximal isometric strength following CR supplementation appear to be restricted to movements performed with a large muscle mass.
ISSN:1050-1606
DOI:10.1123/ijsn.9.2.136