Antibiotic Lock for Treatment of Tunneled Hemodialysis Catheter Bacteremia

Catheter‐related bacteremia is a major cause of morbidity and mortality among catheter‐dependent hemodialysis patients. Microorganism biofilm matrix formation in the catheter is the pathogenic process of this entity. Administration of systemic antibiotics and removal of the offending catheter is the...

Full description

Saved in:
Bibliographic Details
Published in:Seminars in dialysis 2008-11, Vol.21 (6), p.539-541
Main Author: Maya, Ivan D.
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - administration & dosage
Bacteremia - drug therapy
Catheter-Related Infections - drug therapy
Catheterization - adverse effects
Catheterization - instrumentation
Equipment Design
Humans
Renal Dialysis - instrumentation
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Catheter‐related bacteremia is a major cause of morbidity and mortality among catheter‐dependent hemodialysis patients. Microorganism biofilm matrix formation in the catheter is the pathogenic process of this entity. Administration of systemic antibiotics and removal of the offending catheter is the most logical treatment. This article discusses an alternative option, instillation of an antibiotic‐lock solution into the lumen of the catheter plus systemic antibiotic therapy. Recent studies suggest that this strategy could treat the infection and salvage the catheter, thus avoiding the need for further interventional procedures including but not limited to the removal of the catheter, placement of a temporary catheter, and finally placement of a new permanent catheter. The implementation of this effective approach will reduce morbidity and possibly reduce the cost and interventions associated with it.
ISSN:0894-0959
1525-139X
DOI:10.1111/j.1525-139X.2008.00498.x