Successful treatment of disseminated Mycobacterium szulgai infection with ciprofloxacin, rifampicin, and ethambutol

Mycobacterium szulgai, a slow-growing scotochromogenic mycobacterium, was first described by Marks et al. in 1972. Unlike other scotochromogenic mycobacteria, clinical isolates of M. szulgai are usually pathogenic rather than contaminants. Most cases are chronic pulmonary infections, although locali...

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Bibliographic Details
Published in:The Journal of infection 1999-05, Vol.38 (3), p.195-197
Main Authors: Fang, Chi-Tai, Chang, Shan-Chwen, Luh, Kwen-Tay, Chang, Yih-Leong, Hsueh, Po-Ren, Hsieh, Wei-Chuan
Format: Article
Language:English
Subjects:
Adolescent
Aged
Anti-Infective Agents - therapeutic use
Antibiotics, Antitubercular - therapeutic use
Ciprofloxacin - therapeutic use
Drug Therapy, Combination
Ethambutol - therapeutic use
Humans
Male
Middle Aged
Mycobacterium Infections - drug therapy
Mycobacterium Infections - physiopathology
Mycobacterium szulgai
Nontuberculous Mycobacteria
Rifampin - therapeutic use
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Summary:Mycobacterium szulgai, a slow-growing scotochromogenic mycobacterium, was first described by Marks et al. in 1972. Unlike other scotochromogenic mycobacteria, clinical isolates of M. szulgai are usually pathogenic rather than contaminants. Most cases are chronic pulmonary infections, although localized bone and soft tissue infections have also been described. Disseminated M. szulgai infection is extremely rare. Gur et al. reported the only case of disseminated M. szulgai disease with multi-focal osteomyelitis in the literature. Treatment with conventional antituberculous agents was not effective. We report a case with similar clinical manifestations. However, the patient was successfully treated with combination therapy containing ciprofloxacin, which had been reported to be effective for M. szulgi in vitro.
ISSN:0163-4453
1532-2742
DOI:10.1016/S0163-4453(99)90252-9