Prophylactic mupirocin could reduce orthopedic wound infections: 1,044 patients treated with mupirocin compared with 1,260 historical controls

We analyzed the effect of perioperative elimination of nasal carriage of Staphylococcus aureus using mupirocin nasal ointment on the reduction of the postoperative wound infection rate in orthopedics. In an unblinded intervention trial, we compared 1, 044 patients treated with mupirocin (interventio...

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Bibliographic Details
Published in:	Acta orthopaedica 1998-08, Vol.69 (4), p.412-414
Main Authors:	van der Sluis, Albertine J Gernaat, Hoogenboom-Verdegaal, Adriana M, Edixhoven, Philip J, van Rooijen, Neeltje H Spies
Format:	Article
Language:	English
Subjects:	Administration, Intranasal Aged Anti-Bacterial Agents - therapeutic use Antibacterial agents Antibiotic Prophylaxis - methods Antibiotics. Antiinfectious agents. Antiparasitic agents Biological and medical sciences Carrier State - prevention & control Female Humans Infection Control Male Medical sciences Mupirocin - therapeutic use Nose - microbiology Ointments Orthopedic Procedures - adverse effects Pharmacology. Drug treatments Risk Factors Staphylococcal Infections - prevention & control Surgical Wound Infection - etiology Surgical Wound Infection - prevention & control
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