Incidence of childhood-onset bipolar illness in the USA and Europe

The relative incidence of childhood-onset bipolar illness in the USA compared with that in Europe is controversial. We examined this issue in more than 500 out-patients (average age 42 years) with bipolar illness who reported age at onset of first episode, family history, and childhood physical or s...

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Bibliographic Details
Published in:British journal of psychiatry 2008-02, Vol.192 (2), p.150-151
Main Authors: Post, Robert M., Luckenbaugh, David A., Leverich, Gabriele S., Altshuler, Lori L., Frye, Mark A., Suppes, Trisha, Keck, Paul E., McElroy, Susan L., Nolen, Willem A., Kupka, Ralph, Grunze, Heinz, Walden, Joerg
Format: Article
Language:English
Subjects:
Abuse
Adolescents
Adversity
Age of Onset
Bipolar affective disorder
Bipolar disorder
Bipolar Disorder - diagnosis
Bipolar Disorder - epidemiology
Child abuse & neglect
Child sexual abuse
Childhood
Children
Emotional disorders
Europe
Familial factors
Genetics
Germany - epidemiology
Humans
Incidence
Netherlands - epidemiology
Risk Factors
Sexual abuse
Short report
Sickness
United States - epidemiology
USA
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Summary:The relative incidence of childhood-onset bipolar illness in the USA compared with that in Europe is controversial. We examined this issue in more than 500 out-patients (average age 42 years) with bipolar illness who reported age at onset of first episode, family history, and childhood physical or sexual abuse. Childhood or adolescent onset of bipolar illness was reported by 61% of those in the US cohort but by only 30% of those in The Netherlands or Germany. In the USA there was also twice the incidence of childhood adversity and genetic/familial risk for affective disorder. The findings deserve replication and further exploration.
ISSN:0007-1250
1472-1465
DOI:10.1192/bjp.bp.107.037820