Effect of Proximal Arterial Occlusion on the Progression of the Distal Arterial Disease

Purpose To test the hypothesis that a proximal arterial occlusion has a protective effect on the progression of distal arterial disease, assessed by distal runoff resistance score (DRRS). Materials and Methods One hundred and nineteen patients (median age 64 y, male 96%) with a unilateral iliac and/...

Full description

Saved in:
Bibliographic Details
Published in:European journal of vascular and endovascular surgery 2008-03, Vol.35 (3), p.341-345
Main Authors: Park, K.-B, Kim, Y.-W, Lee, K.-B, Kim, D.-I, Kim, D.-K, Do, Y.-S, Shin, S.-W, Cho, S.-K, Choo, S.-W, Choe, Y.-H, Choo, I.-W
Format: Article
Language:English
Subjects:
Aged
Arterial Occlusive Diseases - epidemiology
Arterial Occlusive Diseases - physiopathology
Arteriography
Atherosclerosis
Atherosclerosis - complications
Atherosclerosis - physiopathology
Comorbidity
Disease Progression
Female
Femoral Artery - physiopathology
Humans
Iliac Artery
Lower extremity
Male
Middle Aged
Multivariate Analysis
Popliteal Artery - physiopathology
Retrospective Studies
Risk Factors
Statistics, Nonparametric
Surgery
Tibial Arteries - physiopathology
Vascular Resistance
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Purpose To test the hypothesis that a proximal arterial occlusion has a protective effect on the progression of distal arterial disease, assessed by distal runoff resistance score (DRRS). Materials and Methods One hundred and nineteen patients (median age 64 y, male 96%) with a unilateral iliac and/or femoral arterial occlusion caused by atherosclerosis were analyzed retrospectively. DRRS was assessed on arteriograms of the test limb (with proximal arterial occlusion) and control limb (contralateral limb). Multivariate analysis was performed to determine if a proximal arterial occlusion was an independent risk factor for the development of a difference in the DRRS between the test and control limbs. Results The clinical features of the subjects were claudication in 85%, ankle brachial index 0.52 (median), diabetes in 30% and smoker in 76%. The upper leg DRRS of the test limb was significantly lower in the iliac occlusion group than in the control limb (1.87 ± 1.69 vs 2.85 ± 2.75, p = 0.032). However, multivariate analysis failed to identify any risk factors associated with the difference in DRRS in both limbs. Conclusion There was no evidence that a proximal arterial occlusion was associated with a slower progression of distal arterial disease.
ISSN:1078-5884
1532-2165
DOI:10.1016/j.ejvs.2007.07.027