Nosocomial infection in a neonatal intensive care unit: A prospective study in Taiwan

Background We performed a prospective analysis to determine the prevalence of nosocomial infection and associated risk factors in our neonatal intensive care unit (NICU). Methods Data were collected prospectively on underlying diagnoses, therapeutic interventions/treatments, infections, and outcomes...

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Bibliographic Details
Published in:American journal of infection control 2007-04, Vol.35 (3), p.190-195
Main Authors: Su, Bai-Horng, MD, PhD, Hsieh, Hsin-Yang, MD, Chiu, Hsiao-Yu, MD, Lin, Hsiao-Chuan, MD, Lin, Hung-Chih, MD
Format: Article
Language:English
Subjects:
Biological and medical sciences
Birth Weight
Catheters, Indwelling - adverse effects
Catheters, Indwelling - statistics & numerical data
Cross Infection - epidemiology
Epidemiology. Vaccinations
Female
General aspects
Home Childbirth - statistics & numerical data
Human infectious diseases. Experimental studies and models
Humans
Infant, Newborn
Infection Control
Infectious Disease
Infectious diseases
Intensive Care Units, Neonatal - statistics & numerical data
Medical sciences
Pregnancy
Premature Birth
Prevalence
Prospective Studies
Respiration, Artificial - adverse effects
Respiration, Artificial - statistics & numerical data
Risk Factors
Taiwan - epidemiology
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Summary:Background We performed a prospective analysis to determine the prevalence of nosocomial infection and associated risk factors in our neonatal intensive care unit (NICU). Methods Data were collected prospectively on underlying diagnoses, therapeutic interventions/treatments, infections, and outcomes at 9 am every day from November 2004 through October 2005. Prevalence of nosocomial infection and infection site definitions were according to the National Nosocomial Infections Surveillance system of the Centers for Disease Control and Prevention. Results Among 528 infants enrolled, 60 (11.4%) had 97 nosocomial infections. The survival rate was 92%. The prevalence of nosocomial infections was 17.5%: bloodstream infection, 4.7%, clinical sepsis, 6.3%, pneumonia, 5.1%, urinary tract infections (UTIs), 0.7%, surgical site infection, 0.7%. Intervention-associated infection rate: central intravascular catheter–associated bloodstream infection, 13.7%, TPN-associated bloodstream infection, 15.8%, ventilator-associated pneumonia, 18.6%, surgical site infection 13.7%, urinary catheter–associated UTI, 17.3%. Cut-off values of onset of central intravascular catheter–associated bloodstream infection and ventilator-associated pneumonia were 6 days and 10 days after intervention, respectively. Patients with a birth weight
ISSN:0196-6553
1527-3296
DOI:10.1016/j.ajic.2006.07.004