Role of IGF Signaling in Olfactory Sensory Map Formation and Axon Guidance

Olfactory neurons project their axons to spatially invariant glomeruli in the olfactory bulb, forming an ordered pattern of innervation comprising the olfactory sensory map. A mirror symmetry exists within this map, such that neurons expressing a given receptor typically project to one glomerulus on...

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Bibliographic Details
Published in:Neuron (Cambridge, Mass.) Mass.), 2008-03, Vol.57 (6), p.847-857
Main Authors: Scolnick, Jonathan A., Cui, Kai, Duggan, Cynthia D., Xuan, Shouhong, Yuan, Xiao-bing, Efstratiadis, Argiris, Ngai, John
Format: Article
Language:English
Subjects:
Animals
Axons - drug effects
Axons - physiology
Cerebellum - cytology
Chemotactic Factors - pharmacology
Chromones - pharmacology
DEVBIO
Embryo, Mammalian
Enzyme Inhibitors - pharmacology
Gene Expression Regulation, Developmental - physiology
In Vitro Techniques
Insulin-Like Growth Factor I - genetics
Insulin-Like Growth Factor I - metabolism
Insulin-Like Growth Factor I - pharmacology
Insulin-Like Growth Factor II - genetics
Insulin-Like Growth Factor II - metabolism
Insulin-Like Growth Factor II - pharmacology
Insulin-like growth factors
Ligands
Mice
Mice, Transgenic
MOLNEURO
Morpholines - pharmacology
Mutation - physiology
Neurons
Odors
Olfactory Bulb - cytology
Olfactory Bulb - embryology
Olfactory Bulb - growth & development
Olfactory Marker Protein - genetics
Olfactory Marker Protein - metabolism
Olfactory Pathways - embryology
Olfactory Pathways - physiology
Olfactory Receptor Neurons - cytology
Olfactory Receptor Neurons - drug effects
Olfactory Receptor Neurons - physiology
Rodents
Signal Transduction - physiology
Smell
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