Alcohol Intake and Blood Pressure: A Systematic Review Implementing a Mendelian Randomization Approach

Alcohol has been reported to be a common and modifiable risk factor for hypertension. However, observational studies are subject to confounding by other behavioural and sociodemographic factors, while clinical trials are difficult to implement and have limited follow-up time. Mendelian randomization...

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Bibliographic Details
Published in:PLoS medicine 2008-03, Vol.5 (3), p.e52
Main Authors: Chen, Lina, Davey Smith, George, Harbord, Roger M, Lewis, Sarah J
Format: Article
Language:English
Subjects:
Alcohol Dehydrogenase - genetics
Alcohol Drinking - genetics
Alcohol use
Analysis
Blood pressure
Blood Pressure - genetics
Confidence intervals
Dehydrogenases
Drinking of alcoholic beverages
Enzymes
Epidemiology
Funding
Genetic Predisposition to Disease
Genetics
Genotype & phenotype
Health education (including prevention and promotion)
Humans
Hypertension
Hypertension - enzymology
Hypertension - genetics
Lifestyles
Male
Medical personnel
Observational studies
Pharmacists
Physiological aspects
Polymorphism
Public Health
Public Health and Epidemiology
Socioeconomic determinants of health
Statistical analysis
Systematic review
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