Pregnancy rates after hysteroscopic polypectomy depending on the size or number of the polyps

• Published in: Archives of gynecology and obstetrics 2008-05, Vol.277 (5), p.395-399
• Main Authors: Stamatellos, Ioannis, Apostolides, Aristotelis, Stamatopoulos, Panagiotis, Bontis, John
• Format: Article
• Language: English
• Subjects: Adult; Cohort Studies; Endocrinology; Endometrial Neoplasms - complications; Endometrial Neoplasms - pathology; Endometrial Neoplasms - surgery; Female; Fertility; Gynecology; Human Genetics; Humans; Hysterectomy; Hysteroscopy; Infertility; Infertility, Female - etiology; Infertility, Female - pathology; Infertility, Female - surgery; Medicine; Medicine & Public Health; Obstetrics/Perinatology/Midwifery; Original Article; Polyps; Polyps - complications; Polyps - pathology; Polyps - surgery; Pregnancy; Pregnancy Outcome; Retrospective Studies; Treatment Outcome
• ISSN: 0932-0067; 1432-0711
• DOI: 10.1007/s00404-007-0460-z

Objective To assess the reproductive benefits of hysteroscopic polypectomy in previous infertile women depending on the size or number of the polyps. Design and methods In this retrospective study, from February 2000 to September 2005, totally 83 selected women were included with: a) diagnoses of primary or secondary infertility, endometrial polyp/polyps and abnormal uterine bleeding. Endometrial polyps were diagnosed by transvaginal ultrasound followed by diagnostic hysteroscopy, to confirm diagnosis, and hysteroscopic polypectomy. All 83 subjects who consisted the study group, met inclusion criteria: age under 35 years, at least 12 months of infertility, from 3 to 8 months menstrual disorders (intermenstrual bleeding or spotting, menometrorrhagia or menorrhagia) and from 3 to 18 months of follow-up with attempts to conceive after hysteroscopic polypectomy. The endometrial polyp/polyps appeared to be the only reason to explain their infertility after infertility workup of the couples. There was a comparison of fertility rates after hysteroscopic polypectomy between patients having endometrial polyp ≤ 1 cm and patients with bigger or multiple polyps. Results Of the 83 subjects, all were found to have endometrial polyps in diagnostic hysteroscopy, confirmed at histologic examination after hysteroscopic polypectomy . Among patients of the study group, there were no significant differences in age, type or length of infertility, or follow-up period after the procedure. The mean size of the endometrial polyps was 1.9 ± 1.4.cm. Thirty-one patients had endometrial polyp ≤ 1 cm and 52 patients had bigger or multiple endometrial polyps. Following polypectomy, menstrual pattern was normalized in 91.6% of patients. Spontaneous pregnancy and delivery at term rates, in the total population of the study, increased after the procedure and were 61.4% and 54.2% respectively. There was no statistical difference in fertility rates between patients having polyps ≤ 1 cm and patients having >1 cm polyps or multiple polyps. Spontaneous abortion rate in the first trimester of pregnancy was 6% of the total number of patients and there was no statistical difference between patients with small or bigger/multiple polyps. Type of infertility did not affect fertility rates after hysteroscopic polypectomy. Complication rate after hysteroscopic polypectomy was as low as 2.4%, while recurrence rate of the procedure reached 4.9% of patients. Conclusion Hysteroscopic polypectomy of endometr