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In vitro biostability evaluation of polyurethane composites in acidic, basic, oxidative, and neutral solutions

New and improved properties can often be achieved by compounding two or more different but compatible materials. But, can failure possibility also be increased by such a compounding strategy? In this article, we compared the in vitro biostability of composites with that of the pure polymer. We teste...

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Bibliographic Details
Published in:Journal of biomedical materials research. Part B, Applied biomaterials Applied biomaterials, 2008-05, Vol.85B (2), p.509-518
Main Authors: Lyu, SuPing, Schley, James, Loy, Brian, Luo, Lian, Hobot, Chris, Sparer, Randall, Untereker, Darrel, Krzeszak, Jason
Format: Article
Language:English
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Summary:New and improved properties can often be achieved by compounding two or more different but compatible materials. But, can failure possibility also be increased by such a compounding strategy? In this article, we compared the in vitro biostability of composites with that of the pure polymer. We tested three model composites in oxidative, acidic, basic, and neutral solutions. We found that oxidation degradation was much more profound in the composites than in the corresponding pure polymer. This degradation seemed to be an intrinsic property of composite materials. We also observed the well documented interfacial debonding between filler and matrix and its effects on the mechanical reinforcement of the hydrated composites. The improvements in acid and base resistance were also observed. © 2007 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2008
ISSN:1552-4973
1552-4981
DOI:10.1002/jbm.b.30973