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The effect of exercise on adrenocortical responsiveness of patients with chronic low back pain, controlled for psychological strain

Objective: To investigate the effects of high-intensity aerobic exercise on adrenocortical responsiveness and on standard outcome measures in patients with chronic low back pain. Design: Controlled clinical trial. Setting: Physical therapy department of a university general hospital. Subjects: Sixty...

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Bibliographic Details
Published in:Clinical rehabilitation 2008-04, Vol.22 (4), p.319-328
Main Authors: Chatzitheodorou, Dimitris, Mavromoustakos, Savvas, Milioti, Styliani
Format: Article
Language:English
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Summary:Objective: To investigate the effects of high-intensity aerobic exercise on adrenocortical responsiveness and on standard outcome measures in patients with chronic low back pain. Design: Controlled clinical trial. Setting: Physical therapy department of a university general hospital. Subjects: Sixty-four patients with chronic low back pain were randomly allocated into positive and negative suppression test groups and assigned to exercise protocol. Interventions: Subjects in the positive and negative dexamethasone suppression test groups received a 12-week high-intensity aerobic exercise programme. Main outcome measures: Dexamethasone suppression test as an index of adrenocortical responsiveness, pain measured with the McGill Pain Questionnaire, functional status measured with the Roland Morris Disability Questionnaire, and psychological strain measured with the Hospital Anxiety and Depression Scale. Results: Data analysis in the positive group identified a significant reduction of pain by 30% (t 30 = 11.2, P
ISSN:0269-2155
1477-0873
DOI:10.1177/0269215507079858