HIV-infected children vaccination coverage and safety in a Western European cohort: a retrospective study

Since the implementation of highly active antiretroviral therapy in HIV-infected children, response to scheduled vaccines may determinate future morbidity and mortality. The aims of this study have been to describe the current vaccine coverage, vaccine safety and concordance with vaccine recommendat...

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Bibliographic Details
Published in:International journal of STD & AIDS 2007-05, Vol.18 (5), p.351-353
Main Authors: FERNANDEZ-IBIETA, Maria, RAMOS-AMADOR, José T, AUNON-MARTIN, Ismael
Format: Article
Language:English
Subjects:
Adolescent
Adult
AIDS/HIV
Biological and medical sciences
Child
Child, Preschool
Cohort Studies
Epidemiology. Vaccinations
General aspects
Hepatitis B virus
HIV Infections - complications
HIV Infections - immunology
Human immunodeficiency virus
Human viral diseases
Humans
Immunization Schedule
Immunodeficiencies
Immunodeficiencies. Immunoglobulinopathies
Immunopathology
Infant
Infectious diseases
Mass Vaccination - utilization
Medical sciences
Neisseria meningitidis
Patient Compliance
Retrospective Studies
Spain
Streptococcus pneumoniae
Urban Population
Vaccines - administration & dosage
Varicella-zoster virus
Viral diseases
Viral diseases of the lymphoid tissue and the blood. Aids
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Summary:Since the implementation of highly active antiretroviral therapy in HIV-infected children, response to scheduled vaccines may determinate future morbidity and mortality. The aims of this study have been to describe the current vaccine coverage, vaccine safety and concordance with vaccine recommendations of the 68 HIV-infected children and adolescents followed up in our Unit. Forty-four percent of the children received at least one dose of the oral polio vaccine (OPV). Only 9.1% needed and received a second set of hepatitis B virus immunization because of low vaccine response. Only 14.7% were vaccinated against varicella. Coverages of 82.3% and 100% have been reached with the 23-valent and the 7-valent pneumococcal vaccines, respectively. Meningococcal conjugated vaccine uptake was moderate (80.8%). Influenza annual vaccination coverage was poor: only 22.7% had well-documented yearly vaccines. In our experience, vaccine coverage is lower in those vaccines administered in primary care centres compared with the immunizations given at the hospital. OPV administration did not cause any adverse effect in the children or in their families. Vaccine coverage in HIV-infected children was suboptimal.
ISSN:0956-4624
1758-1052
DOI:10.1258/095646207780749763