Caffeine and 35% carbon dioxide challenge tests in panic disorder

Our aim was to compare the demographic and clinical features of panic disorder (PD) patients with agoraphobia—DSM‐IV—who had a panic attack after both an oral caffeine and the 35% carbon dioxide (CO2) challenge tests (responsive group) and compare them with PD patients who did not have a panic attac...

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Bibliographic Details
Published in:Human psychopharmacology 2007-06, Vol.22 (4), p.231-240
Main Authors: Nardi, Antonio E., Valença, Alexandre M., Lopes, Fabiana L., de-Melo-Neto, Valfrido L., Freire, Rafael C., Veras, Andre B., Nascimento, Isabella, King, Anna Lucia, Soares-Filho, Gastão L., Mezzasalma, Marco A., Zin, Walter A.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age of Onset
Agoraphobia - diagnosis
Agoraphobia - epidemiology
Agoraphobia - psychology
anxiety disorder
Caffeine
Carbon Dioxide
Central Nervous System Stimulants
coffee
diagnosis
Double-Blind Method
Female
Humans
Male
Middle Aged
panic attacks
Panic Disorder - diagnosis
Panic Disorder - epidemiology
Panic Disorder - psychology
Psychiatric Status Rating Scales
respiration
respiratory test
Socioeconomic Factors
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Summary:Our aim was to compare the demographic and clinical features of panic disorder (PD) patients with agoraphobia—DSM‐IV—who had a panic attack after both an oral caffeine and the 35% carbon dioxide (CO2) challenge tests (responsive group) and compare them with PD patients who did not have a panic attack after both tests (non‐responsive group). We examined 83 PD patients submitted to a 35% CO2 test and to an oral caffeine (480 mg) intake within 1 week interval. A panic attack was induced in 51 (61.4%) patients during the CO2 test (χ2 = 31.67, df = 1, p 
ISSN:0885-6222
1099-1077
DOI:10.1002/hup.840