Multiple Juvenile Xanthogranulomas in a 13‐Year‐Old

• Published in: Pediatric dermatology 2007-05, Vol.24 (3), p.238-240
• Main Authors: Redbord, Kelley Pagliai, Sheth, Anita P.
• Format: Article
• Language: English
• Subjects: Adolescent; Biological and medical sciences; Biopsy; Dermatology; Female; Giant Cells - pathology; Humans; Lymphocytes - pathology; Macrophages - pathology; Medical sciences; Skin - pathology; Tumors of the skin and soft tissue. Premalignant lesions; Xanthogranuloma, Juvenile - pathology
• ISSN: 0736-8046; 1525-1470
• DOI: 10.1111/j.1525-1470.2007.00393.x

:  A 13‐year‐old Caucasian girl presented with a 1½ month history of multiple, asymptomatic, discrete, orange‐yellow to skin‐colored, dome‐shaped, smooth, 3 to 6 mm papules on the arms, legs, trunk, and buttock. Pathology showed a dermal infiltrate of Touton‐type giant cells, scattered lymphocytes, and macrophages. The patient was diagnosed with juvenile xanthogranuloma. We present this patient because of the uncommon presentation of multiple juvenile xanthogranulomas in a 13‐year‐old. Although juvenile xanthogranuloma generally occurs in infancy, it must be included in the differential diagnosis for an older child. This entity can less frequently occur in adults and typically a solitary lesion is found. Multiple juvenile xanthogranuloma is rare in older children and adults. Work‐up should include a thorough review of systems, physical examination, and ophthalmology examination. Pediatricians and dermatologists should be aware that juvenile xanthogranulomas might occur in older children.