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Orthokeratology in low myopia. Part 1: efficacy and predictability

Modern orthokeratology (ortho-k) using reverse geometry lens designs is being widely used for myopia reduction world-wide although there has been no well-controlled clinical trial of this procedure. This paper reports on the efficacy and predictability of an ortho-k procedure using the OK-74 lens de...

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Bibliographic Details
Published in:Contact lens & anterior eye 2000, Vol.23 (3), p.77-89
Main Authors: Lui, Wai-On, Edwards, Marion H.
Format: Article
Language:English
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Summary:Modern orthokeratology (ortho-k) using reverse geometry lens designs is being widely used for myopia reduction world-wide although there has been no well-controlled clinical trial of this procedure. This paper reports on the efficacy and predictability of an ortho-k procedure using the OK-74 lens design (now known as OK-704). Methods. We carried out a 100-day, controlled, randomised clinical trial in which 14 subjects underwent ortho-k and a further 14 were fitted with aligned rigid contact lenses. The mean reduction in myopia was 1.50 (SD 0.45) D in the ortho-k group and 0.01 (SD 0.20) D in the control group. Unaided vision improved by −0.64 (SD 0.22) logMAR units in the ortho-k group, compared with −0.09 (SD 0.11) units in the control group. Variables which correlated with refractive change were corneal thickness, p-value of the nasal semi-meridian and the difference between central and peripheral corneal powers. A multiple factors model can account for 72% of the refractive change. Ortho-k using the OK-74 lens design achieved an average myopia reduction of 1.50 D. The model developed can provide an estimate of the refractive change likely to occur in ortho-k, a matter of importance to both clinician and patient.
ISSN:1367-0484
1476-5411
DOI:10.1016/S1367-0484(00)80016-8