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Prospects for Organ and Tissue Replacement
Damage or loss of a tissue or organ is common, costly, and tragic. Advances in mechanical artificial organs and organ transplantation have improved the treatment of organ failure, and advances in molecular immunology, tissue engineering, and stem cell biology offer the promise of even better therape...
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Published in: | JAMA : the journal of the American Medical Association 2001-02, Vol.285 (5), p.573-576 |
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container_start_page | 573 |
container_title | JAMA : the journal of the American Medical Association |
container_volume | 285 |
creator | Niklason, Laura E Langer, Robert |
description | Damage or loss of a tissue or organ is common, costly, and tragic. Advances
in mechanical artificial organs and organ transplantation have improved the
treatment of organ failure, and advances in molecular immunology, tissue engineering,
and stem cell biology offer the promise of even better therapeutic modalities
for treating organ failure in the future. Enhancement of immune tolerance
of transplanted tissues, improved understanding of cellular differentiation
and tissue development, and advances in biomaterials may enable the de novo
creation of implantable tissue and organs for transplantation. Innovative
techniques for prevention and treatment of tissue loss and organ failure should
improve the quality and length of life. |
doi_str_mv | 10.1001/jama.285.5.573 |
format | article |
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in mechanical artificial organs and organ transplantation have improved the
treatment of organ failure, and advances in molecular immunology, tissue engineering,
and stem cell biology offer the promise of even better therapeutic modalities
for treating organ failure in the future. Enhancement of immune tolerance
of transplanted tissues, improved understanding of cellular differentiation
and tissue development, and advances in biomaterials may enable the de novo
creation of implantable tissue and organs for transplantation. Innovative
techniques for prevention and treatment of tissue loss and organ failure should
improve the quality and length of life.</description><identifier>ISSN: 0098-7484</identifier><identifier>EISSN: 1538-3598</identifier><identifier>DOI: 10.1001/jama.285.5.573</identifier><identifier>PMID: 11176861</identifier><identifier>CODEN: JAMAAP</identifier><language>eng</language><publisher>Chicago, IL: American Medical Association</publisher><subject>Animals ; Artificial Organs - trends ; Biocompatible Materials ; Biological and medical sciences ; Forecasting ; Humans ; Immunology ; Medical research ; Medical sciences ; Medical technology ; Miscellaneous ; Organ Transplantation - trends ; Prostheses ; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) ; Research - trends ; Stem cells ; Tissue Transplantation - trends ; Transplants & implants</subject><ispartof>JAMA : the journal of the American Medical Association, 2001-02, Vol.285 (5), p.573-576</ispartof><rights>2001 INIST-CNRS</rights><rights>Copyright American Medical Association Feb 7, 2001</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a325t-fdbb426f6a89c710ddfa2ff8d1aa3ae1c53c9e82be6f2864eec962cd198a06dd3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=874335$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11176861$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Niklason, Laura E</creatorcontrib><creatorcontrib>Langer, Robert</creatorcontrib><title>Prospects for Organ and Tissue Replacement</title><title>JAMA : the journal of the American Medical Association</title><addtitle>JAMA</addtitle><description>Damage or loss of a tissue or organ is common, costly, and tragic. Advances
in mechanical artificial organs and organ transplantation have improved the
treatment of organ failure, and advances in molecular immunology, tissue engineering,
and stem cell biology offer the promise of even better therapeutic modalities
for treating organ failure in the future. Enhancement of immune tolerance
of transplanted tissues, improved understanding of cellular differentiation
and tissue development, and advances in biomaterials may enable the de novo
creation of implantable tissue and organs for transplantation. Innovative
techniques for prevention and treatment of tissue loss and organ failure should
improve the quality and length of life.</description><subject>Animals</subject><subject>Artificial Organs - trends</subject><subject>Biocompatible Materials</subject><subject>Biological and medical sciences</subject><subject>Forecasting</subject><subject>Humans</subject><subject>Immunology</subject><subject>Medical research</subject><subject>Medical sciences</subject><subject>Medical technology</subject><subject>Miscellaneous</subject><subject>Organ Transplantation - trends</subject><subject>Prostheses</subject><subject>Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. 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in mechanical artificial organs and organ transplantation have improved the
treatment of organ failure, and advances in molecular immunology, tissue engineering,
and stem cell biology offer the promise of even better therapeutic modalities
for treating organ failure in the future. Enhancement of immune tolerance
of transplanted tissues, improved understanding of cellular differentiation
and tissue development, and advances in biomaterials may enable the de novo
creation of implantable tissue and organs for transplantation. Innovative
techniques for prevention and treatment of tissue loss and organ failure should
improve the quality and length of life.</abstract><cop>Chicago, IL</cop><pub>American Medical Association</pub><pmid>11176861</pmid><doi>10.1001/jama.285.5.573</doi><tpages>4</tpages></addata></record> |
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ispartof | JAMA : the journal of the American Medical Association, 2001-02, Vol.285 (5), p.573-576 |
issn | 0098-7484 1538-3598 |
language | eng |
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source | JAMA Network |
subjects | Animals Artificial Organs - trends Biocompatible Materials Biological and medical sciences Forecasting Humans Immunology Medical research Medical sciences Medical technology Miscellaneous Organ Transplantation - trends Prostheses Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Research - trends Stem cells Tissue Transplantation - trends Transplants & implants |
title | Prospects for Organ and Tissue Replacement |
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